Literature DB >> 36072214

Recent Advances in the Management of Polycystic Ovary Syndrome: A Review Article.

Shivani Akre1, Kapil Sharma1, Swarupa Chakole2, Mayur B Wanjari3.   

Abstract

Polycystic ovarian syndrome (PCOS) is an endocrine disorder. This condition is characterized by chronic anovulation and ovarian dysfunction, unlike other ovulation disorders when the ovaries are non-functional or abnormal. Currently, most therapy is centred on the patient's primary complaint. Treatment focuses on reducing hyperandrogenism symptoms, restoring menstrual regularity, and achieving conception. In treating infertility caused by polycystic ovarian syndrome, letrozole (an aromatase inhibitor) appears to be more successful than clomiphene citrate (an anti-estrogen and a reference infertility drug). When provided by a multidisciplinary team, it can help patients maintain appropriate lifestyle changes, such as reducing body fat, increasing metabolism, and enhancing reproductive health. Compound oral contraceptives are the most common kind of androgen inhibitor and are the preferred therapy for menstrual disruption in PCOS patients who do not want to get pregnant. Weight loss should be prioritized for women with PCOS since a healthy, balanced diet combined with regular exercise can boost metabolism, increase insulin sensitivity, and aid weight loss safely. This will improve their physical health. Other than reproductive symptoms, PCOS symptoms include insulin resistance (IR), metabolic syndrome (MS), and chronic low-grade inflammation. Our understanding of the pathophysiological process, diagnosis, and therapy of PCOS has advanced recently.
Copyright © 2022, Akre et al.

Entities:  

Keywords:  combined oral contraceptive pills; hyperandrogenism; lifestyle interventions; menstrual irregularity; pcos

Year:  2022        PMID: 36072214      PMCID: PMC9440853          DOI: 10.7759/cureus.27689

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  20 in total

1.  Polycystic ovary syndrome: a review of treatment options with a focus on pharmacological approaches.

Authors:  Uche Anadu Ndefo; Angie Eaton; Monica Robinson Green
Journal:  P T       Date:  2013-06

Review 2.  CLINICAL PRACTICE. Polycystic Ovary Syndrome.

Authors:  Christopher R McCartney; John C Marshall
Journal:  N Engl J Med       Date:  2016-07-07       Impact factor: 91.245

3.  Visceral adiposity index levels in overweight and/or obese, and non-obese patients with polycystic ovary syndrome and its relationship with metabolic and inflammatory parameters.

Authors:  U Durmus; C Duran; S Ecirli
Journal:  J Endocrinol Invest       Date:  2016-11-12       Impact factor: 4.256

Review 4.  Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis.

Authors:  John A Barry; Mallika M Azizia; Paul J Hardiman
Journal:  Hum Reprod Update       Date:  2014-03-30       Impact factor: 15.610

5.  Erratum. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.

Authors:  Helena J Teede; Marie L Misso; Michael F Costello; Anuja Dokras; Joop Laven; Lisa Moran; Terhi Piltonen; Robert J Norman
Journal:  Hum Reprod       Date:  2019-02-01       Impact factor: 6.918

Review 6.  Infertility management in women with polycystic ovary syndrome: a review.

Authors:  Anita Cunha; Ana Margarida Póvoa
Journal:  Porto Biomed J       Date:  2021-01-26

Review 7.  The Complementary and Alternative Medicine for Polycystic Ovary Syndrome: A Review of Clinical Application and Mechanism.

Authors:  Li-Yan Jia; Jia-Xing Feng; Juan-Li Li; Fang-Yuan Liu; Liang-Zhen Xie; Shou-Juan Luo; Feng-Juan Han
Journal:  Evid Based Complement Alternat Med       Date:  2021-02-26       Impact factor: 2.629

Review 8.  Genetic, hormonal and metabolic aspects of PCOS: an update.

Authors:  V De Leo; M C Musacchio; V Cappelli; M G Massaro; G Morgante; F Petraglia
Journal:  Reprod Biol Endocrinol       Date:  2016-07-16       Impact factor: 5.211

Review 9.  Hormonal contraception in women with polycystic ovary syndrome: choices, challenges, and noncontraceptive benefits.

Authors:  Anderson Sanches de Melo; Rosana Maria Dos Reis; Rui Alberto Ferriani; Carolina Sales Vieira
Journal:  Open Access J Contracept       Date:  2017-02-02
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