Literature DB >> 36071531

Correction: RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma.

Xueping Jiang1, Yangyi Li1, Nannan Zhang1, Yanping Gao1, Linzhi Han1, Shuying Li1, Jiali Li1, Xingyu Liu1, Yan Gong2,3, Conghua Xie4,5,6.   

Abstract

Entities:  

Year:  2022        PMID: 36071531      PMCID: PMC9450415          DOI: 10.1186/s13578-022-00882-8

Source DB:  PubMed          Journal:  Cell Biosci        ISSN: 2045-3701            Impact factor:   9.584


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Correction: Cell Biosci (2021) 11:74 https://doi.org/10.1186/s13578-021-00586-5

In this article [1], the representative images of CD4 and CD8 staining for tumor IHC were carelessly repeated in Fig. 8. The corrected Fig. 8 should have appeared as shown in this correction.
Fig. 8

RRM2 silencing has anti-tumor effects and enhances CD8 + T cells infiltrations in Lewis mice model. Lewis mice were injected with LV-NC and LV-siRRM2 infected LLC cells. a The tumor volumes were measured every 3 days and depicted in the line chart. b, c Representative IVIS spectrum imaging for tumor-bearing mice. The fluorescence radiance comparison between LLC-LV-NC and LLC-LV-siRRM2 groups. d, e Representative fow cytometry of CD4 + and CD8 + T cells in spleens and tumors. Quantitative analysis of CD4 + and CD8 + T cells in spleens and tumors. f, g Representative image of CD4 and CD8 staining for spleens and tumors by IHC. Scale bar: 100 μm. *p < 0.05, **p < 0.01, ns: not significant

RRM2 silencing has anti-tumor effects and enhances CD8 + T cells infiltrations in Lewis mice model. Lewis mice were injected with LV-NC and LV-siRRM2 infected LLC cells. a The tumor volumes were measured every 3 days and depicted in the line chart. b, c Representative IVIS spectrum imaging for tumor-bearing mice. The fluorescence radiance comparison between LLC-LV-NC and LLC-LV-siRRM2 groups. d, e Representative fow cytometry of CD4 + and CD8 + T cells in spleens and tumors. Quantitative analysis of CD4 + and CD8 + T cells in spleens and tumors. f, g Representative image of CD4 and CD8 staining for spleens and tumors by IHC. Scale bar: 100 μm. *p < 0.05, **p < 0.01, ns: not significant
  1 in total

1.  RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma.

Authors:  Xueping Jiang; Yangyi Li; Nannan Zhang; Yanping Gao; Linzhi Han; Shuying Li; Jiali Li; Xingyu Liu; Yan Gong; Conghua Xie
Journal:  Cell Biosci       Date:  2021-04-15       Impact factor: 9.584

  1 in total

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