| Literature DB >> 36071382 |
Louise Ziegler1, Håkan Wallén2, Sara Aspberg2, Ulf de Faire3, Bruna Gigante4.
Abstract
Entities:
Year: 2022 PMID: 36071382 PMCID: PMC9450387 DOI: 10.1186/s12883-022-02831-x
Source DB: PubMed Journal: BMC Neurol ISSN: 1471-2377 Impact factor: 2.903
Number of ischemic strokes and B/T ratio level in subjects with and without atrial fibrillation
| Never AF | AF | P | |
|---|---|---|---|
| Total number | 2748 | 445 | - |
| Stroke | 140 (5%) | 63 (14%) | <0.0001 |
| B/T ratio | 1.58 (1.54-1.61) | 1.58 (1.54-1.61) | 0.94 |
Number of participants with ischemic stroke during follow-up (%) and levels of the B/T ratio presented as median (IQR) in subjects with AF (prevalent or incident) compared to those without (Never AF)
Risk of incident atrial fibrillation associated with the B/T ratio
| B/T ratio | Crude | P | Adjusted | P |
|---|---|---|---|---|
| ≤25th perc | 1.00 (ref) | - | 1.00 (ref) | |
| 25-50th perc | 0.93 (0.71-1.23) | 0.65 | 0.89 (0.67-1.17) | 0.41 |
| 50-75th perc | 1.01 (0.77-1.32) | 0.93 | 0.92 (0.70-1.21) | 0.57 |
| >75th perc | 1.00 (0.77-1.32) | 0.94 | 0.86 (0.65-1.14) | 0.30 |
| ≤median | 1.00 (ref) | - | 1.00 (ref) | |
| >median | 1.04 (0.86-1.26) | 0.67 | 0.94 (0.78-1.15) | 0.59 |
Risk of incident AF associated with the B/T ratio, categorized into percentiles (perc) and dichotomized at the median, analyzed by Cox regression and expressed as HR (95% CI). Multivariate analysis adjusted for sex, hypertension, BMI, and left ventricular hypertrophy. Participants with prevalent AF at baseline were excluded from this analysis. Missing data on left ventricular hypertrophy (n = 6)
Fig. 1Risk of future ischemic stroke associated with the B/T ratio > median in subjects with and without a diagnosis of AF analyzed by Cox regression and expressed as hazard ratio with 95% confidence interval
Fig. 2Cumulative incidence of AF in subjects without prevalent AF at baseline stratifed by the B/T ratio dichotomized at the median