Arshdeep Singh1, Vandana Midha2, Ramit Mahajan1, Shruti Verma1, Chandan Kakkar3, Jasmine Grover1, Dharmatma Singh1, Ramandeep Kaur1, Abhishek Masih1, Namita Bansal4, Catherine Wall5, Ajit Sood6. 1. Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. 2. Department of Internal Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. 3. Department of Radiology and Radiodiagnosis, Dayanand Medical College, Ludhiana, Punjab, India. 4. Research and Development Centre, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. 5. Department of Medicine and Department of Human Nutrition, University of Otago, Christchurch, New Zealand. 6. Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. ajitsood10@gmail.com.
Abstract
BACKGROUND: Inflammatory bowel disease (IBD) is associated with an increased risk of malnutrition and sarcopenia. AIMS: To evaluate the nutritional status of patients with IBD and determine the threshold values of different parameters of nutritional assessment to identify malnutrition. METHODS: This was a single-centre cross-sectional analysis of adult patients with IBD [ulcerative colitis (UC) and Crohn's disease (CD)] who underwent anthropometry [body mass index (BMI), mid upper arm circumference (MUAC) and triceps-fold thickness (TSF)], body composition analysis and assessment for sarcopenia [hand-grip strength and skeletal muscle index (SMI) at L3 vertebral level)]. Age- and gender-matched healthy adults served as controls. Malnutrition was defined according to the European Society of Clinical Nutrition and Metabolism (ESPEN) criteria. RESULTS: A total of 406 patients [336 (82.76%) UC and 70 (17.24%) CD; mean age 40.56 ± 13.67 years; 215 (52.95%) males] with IBD and 100 healthy controls (mean age 38.69 ± 10.90 years; 56 (56%) males) were enrolled. The mean BMI, MUAC, TSF thickness, fat and lean mass, hand-grip strength, and SMI at L3 vertebral level were lower in patients with IBD compared to controls. The prevalence of malnutrition was similar in UC and CD [24.40% (n = 82) and 28.57% (n = 20), respectively (p = 0.46)]. Thresholds for fat mass in females (15.8 kg) and visceral fat index in males (0.26) were both sensitive and specific to detect malnutrition. The cutoff values of MUAC and TSF thickness to identify malnutrition were 23.25 cm and 25.25 cm, and 16.50 mm and 8.50 mm, in females and males, respectively. CONCLUSION: Malnutrition and sarcopenia were common in patients with IBD, with the prevalence being similar in patients with both UC and CD.
BACKGROUND: Inflammatory bowel disease (IBD) is associated with an increased risk of malnutrition and sarcopenia. AIMS: To evaluate the nutritional status of patients with IBD and determine the threshold values of different parameters of nutritional assessment to identify malnutrition. METHODS: This was a single-centre cross-sectional analysis of adult patients with IBD [ulcerative colitis (UC) and Crohn's disease (CD)] who underwent anthropometry [body mass index (BMI), mid upper arm circumference (MUAC) and triceps-fold thickness (TSF)], body composition analysis and assessment for sarcopenia [hand-grip strength and skeletal muscle index (SMI) at L3 vertebral level)]. Age- and gender-matched healthy adults served as controls. Malnutrition was defined according to the European Society of Clinical Nutrition and Metabolism (ESPEN) criteria. RESULTS: A total of 406 patients [336 (82.76%) UC and 70 (17.24%) CD; mean age 40.56 ± 13.67 years; 215 (52.95%) males] with IBD and 100 healthy controls (mean age 38.69 ± 10.90 years; 56 (56%) males) were enrolled. The mean BMI, MUAC, TSF thickness, fat and lean mass, hand-grip strength, and SMI at L3 vertebral level were lower in patients with IBD compared to controls. The prevalence of malnutrition was similar in UC and CD [24.40% (n = 82) and 28.57% (n = 20), respectively (p = 0.46)]. Thresholds for fat mass in females (15.8 kg) and visceral fat index in males (0.26) were both sensitive and specific to detect malnutrition. The cutoff values of MUAC and TSF thickness to identify malnutrition were 23.25 cm and 25.25 cm, and 16.50 mm and 8.50 mm, in females and males, respectively. CONCLUSION: Malnutrition and sarcopenia were common in patients with IBD, with the prevalence being similar in patients with both UC and CD.
Authors: Eanna Ryan; Daniel McNicholas; Ben Creavin; Michael Eamon Kelly; Tom Walsh; David Beddy Journal: Inflamm Bowel Dis Date: 2019-01-01 Impact factor: 5.325
Authors: Kelly C Cushing; Hamed Kordbacheh; Michael S Gee; Avinash Kambadakone; Ashwin N Ananthakrishnan Journal: J Crohns Colitis Date: 2018-08-29 Impact factor: 9.071
Authors: María José Casanova; Maria Chaparro; Begoña Molina; Olga Merino; Ricardo Batanero; Carmen Dueñas-Sadornil; Pilar Robledo; Ana María Garcia-Albert; Maria Bienvenida Gómez-Sánchez; Xavier Calvet; Maria Del Roser Trallero; Miguel Montoro; Iria Vázquez; Mara Charro; Amaya Barragán; Francisco Martínez-Cerezo; Isabel Megias-Rangil; José María Huguet; Ezequiel Marti-Bonmati; Marta Calvo; Mariana Campderá; Margarita Muñoz-Vicente; Angel Merchante; Ansel David Ávila; Pilar Serrano-Aguayo; Ruth De Francisco; Daniel Hervías; Luis Bujanda; Gloria Esther Rodriguez; Luisa Castro-Laria; Manuel Barreiro-de Acosta; Manuel Van Domselaar; Patricia Ramirez de la Piscina; Javier Santos-Fernández; Alicia Algaba; Sandra Torra; Liliana Pozzati; Pilar López-Serrano; Maria Del Rosario Arribas; Maria Luisa Rincón; Andrés Camilo Peláez; Elena Castro; Antonio García-Herola; Cecilio Santander; Moisés Hernández-Alonso; Elisa Martín-Noguerol; María Gómez-Lozano; Tamara Monedero; Albert Villoria; Ariadna Figuerola; Andrés Castaño-García; Jesús M Banales; Laura Díaz-Hernández; Federico Argüelles-Arias; Javier López-Díaz; Isabel Pérez-Martínez; Noelia García-Talavera; Olivia Karina Nuevo-Siguairo; Sabino Riestra; Javier P Gisbert Journal: J Crohns Colitis Date: 2017-12-04 Impact factor: 9.071