Literature DB >> 36064669

COVID-19 vaccine hesitancy among health care worker-parents (HCWP) in Puducherry, India and its implications on their children: A cross sectional descriptive study.

Pratik Sarkar1, Venkatesh Chandrasekaran2, Dhandapany Gunasekaran1, Palanivel Chinnakali3.   

Abstract

BACKGROUND: Vaccine hesitancy affects immunization programs worldwide and can impact vaccine coverage and fight against Coronavirus disease 2019 (COVID-19) too.
OBJECTIVES: Primary objectives: To find out the magnitude of COVID-19 vaccine hesitancy among the Health Care Worker Parents (HCWPs), the reasons for vaccine hesitancy, and their perceptions regarding COVID-19 vaccination of their children. SECONDARY
OBJECTIVE: To analyze the clinic-socio-demographic correlates of COVID-19 vaccine hesitancy among HCWPs.
METHODS: This was a cross sectional descriptive study. Health care workers who are parents were invited to participate in the study. Details about COVID vaccination status, COVID-19 illness of HCWPS and family members and its outcomes , reasons for not getting vaccinated, willingness to vaccinate their children, reasons for not willing to vaccinate their children, their responses to vaccine hesitancy survey (VHS) questionnaire and Modified Oxford COVID-19 vaccine hesitancy scale (MOVHS) were collected and analyzed using descriptive statistics.
RESULTS: A total of 269 HCWPs participated in the study. Of the HCWPs, 97% had completed their COVID-19 vaccination schedule. Majority stated that they would vaccinate their children when it is available. Although majority of the responses were positive or towards agreement, there were some striking variations in the responses among some sections of HCWPs. Positive responses to the questionnaire were associated with higher self-vaccination and a decision to vaccinate their children.
CONCLUSION: Vaccine hesitancy was less common among HCWPs in our study. A section of the HCWPs might be disproportionately more hesitant than others. Majority were in favor of vaccinating their children.
Copyright © 2022 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  COVID-19; Children; Health Care Workers; Hesitancy; Vaccination

Mesh:

Substances:

Year:  2022        PMID: 36064669      PMCID: PMC9420929          DOI: 10.1016/j.vaccine.2022.08.051

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   4.169


Introduction

Globally there have been more than 584 million cases of COVID-19 recorded and more than 6 million deaths as on 10th August 2022 and more than 12 billion doses of COVID-19 vaccine have been administered as on 8th August 2022. [1] India accounted for more than 44 million cases and over 500,000 deaths as on 10th August 2022. [1]Significant herd immunity in the community is needed to control the pandemic and the only way to safely attain it is through mass vaccination. [2] However, recent studies have shown that vaccine hesitancy in the community is one of the significant hindering factors for inadequate vaccination. [3], [4], [5] Health care workers (HCW) have the unique opportunity of being role models in the vaccination efforts and can spearhead the vaccination drive so that vaccination uptake increases even among the general population. However, it has been reported that even HCWs have vaccine hesitancy to the tune of 22.51 % out of 76,471 HCWs which can compromise their protection and that of their family members. [6] This hesitancy can be a result of a lack of trust, misinformation from social media, alternate beliefs, and experiences of adverse events during previous vaccination. [7] It is not known to what extent vaccine hesitancy is prevalent among HCWs in India and how it affects their family members, especially their children. Therefore, we aimed to describe the vaccine hesitancy for COVID-19 vaccine among HCWPs of a tertiary care institute in Puducherry, India. The primary objectives of our study are to find out the magnitude of COVID-19 vaccine hesitancy among the Health Care Worker Parents (HCWPs), the reasons for vaccine hesitancy, and to study their perceptions regarding COVID-19 vaccination of their children. The secondary objective is to analyze the clinic-socio-demographic correlates of COVID-19 vaccine hesitancy among HCWPs.

Methodology:

This was a cross sectional descriptive part of a mixed methods study involving health care workers who are also parents. For the purpose of this study, we have defined health care worker as any person (doctors, nurses, pharmacists, dieticians, lab technicians, OT technicians/assistants, ward attendants, sanitary workers, etc.) whose activities involve contact with patients or with body fluid of patients in a health care or laboratory setting. The definition of health care worker has been adapted from Centre for Disease Control and Prevention‘s “Public Health Service Guidelines for the Management of Health Care Worker Exposures to HIV and Recommendations for Post Exposure Prophylaxis” (MMWR 1998, Vol 47, RR-7). We have defined Health Care Worker-Parent(s) as those HCW who have a living child or children. Assuming the proportion of health care workers with vaccine hesitancy to be 30 % based on published literature with 5 % absolute precision and 95 % confidence level, the required sample size would be 270. [8], [9] Sample size calculated from openepi.com. Depending on the proportion of doctors, nurses, and other health care workers, an equivalent proportion of HCWPs were recruited to make up the sample size as per convenience. Informed written consent was obtained from the participants. The study was approved by our Institute‘s scientific advisory committee and ethics committee for human studies (JIP/IEC/2021/270). Information pertaining to socio demographics including age, sex, religion, number of family members in the household, nature of their residence, and socioeconomic status, was collected. For the purpose of our study we have defined vaccine hesitancy as delay in acceptance or refusal of vaccination despite the availability of vaccination service. [10] Vaccination service was available at the health facility itself on all days of the week free of cost. To assess vaccine hesitancy, a ten point validated vaccine hesitancy survey (VHS) questionnaire, developed by the SAGE working group of the World Health Organization and validated in a real world setting was used. [11], [12] Other set of questions in the form of investigator administered proforma was used to collect data regarding the inherent awareness of the benefits or dangers of the vaccine, health status (including hospitalization for COVID- 19 at any time in the past and the treatment details) and vaccination status of the family members, the reasons for postponing vaccination or hesitancy in vaccination, perceptions regarding child vaccination were recorded. For perception regarding child COVID-19 vaccination, a modified Oxford COVID- 19 vaccine hesitancy scale (MOVHS) was used. [13] The questionnaires (see appendix) were reviewed by two experts for content validity and was then translated to the local language Tamil and again back translated to English to ensure that the actual meaning is retained in both languages. Health care workers who were parents and who were willing to participate in the study were included. Those who had current COVID illness and hospitalized or in home isolation or home quarantine, not being present on the day of interview or unable to give sufficient information were excluded (Fig. 1 ). The data from the interview was entered into a data collection proforma from which the information was exported to excel chart and analysed using SPSS software. Categorical variables like gender, religion, socioeconomic status, health care worker type vaccination status, COVID-19 status, magnitude of vaccine hesitancy (defined as failure to get vaccinated or unduly delaying it due to any reason) is expressed as proportion and analysed, using chi square test. Association between vaccine hesitancy in HCWP and perceptions to child vaccination was explored using chi square test and a P value of less than 0.05 was considered for statistical significance.
Fig. 1

Study Flow Diagram.

Study Flow Diagram.

Results:

A total of 269 HCWPs were included (Fig. 1). Out of the 269 HCWPs, 125 (46 %) were males and the rest were females. Nurses constituted the majority of HCWPs accounting for about one third of the study population, followed by medical social workers (MSWs) and miscellaneous staff, doctors including research scholars, housekeeping staff, security personnel, pharmacists and technicians and engineers combined in that order (Table 1 ). The miscellaneous staff included counsellors, out patient department attendants, dressers, physiotherapists, and scholars pursuing Master of Public Health. Only eight HCWPs were not fully vaccinated against COVID-19 accounting for 3 % of the HCWPs. Of these eight individuals, males and females were equal in number, nurses accounted for five HCWPs followed by two housekeeping staff and one security personnel (Table 2 ). Recent COVID-19 infection, worries about adverse effects of the vaccine and recent abortion kept three participants from receiving the vaccination. When queried whether they would vaccinate their children when COVID-19 vaccination is rolled out for their children, 229 (85.13 %) HCWPs said they would vaccinate their children, 34 (12.6 %) said they wouldn’t and 6 (2.2 %) said they were not sure (Table 3 ). Of the HCWPs 100 % of MSWs and miscellaneous staff and pharmacists said they would get their children vaccinated. A higher proportion of security personnel and housekeeping staff said they wouldn’t vaccinate their children (Table 3). The reasons mentioned for not vaccinating their children is given in Table 4 . On analysing the COVID-19 infection status among the participants, it was found that the doctors were most often infected (56.8 %) and technicians/engineers were not affected at all.
Table 1

Sociodemographic characteristics of the Health care-worker parents in a tertiary care institute, Puducherry, India, 2022.

SociodemographicCharacteristicsTotal N (%)
Gender
Male125 (45.9)
Female144 (54.1)
ResidencePuducherry262 (97.4)
Others7 (2.6)
OccupationDoctors/PhD scholars37 (13.8)
Nursing officers79 (29.4)
Medical Social Workers and Miscellaneous staff50 (18.6)
Housekeeping staff37 (13.8)
Security personnel31 (11.5)
Pharmacists28 (10.4)
Technicians/Engineers7 (2.6)
Table 2

COVID Vaccination status of study participants.

CharacteristicsVaccination Status
YESN (%)NON (%)
Completed two doses of vaccine prior to start of the study261 (97)8 (3)
GenderMale121 (46.3)4 (50)

Female140 (53.6)4 (50)
ResidencePuducherry254 (97.3)8 (1 0 0)
Others7 (2.6)0
OccupationDoctors/PhD scholars37 (14.1)0
Nursing officers74 (28.3)5 (62.5)
Medical Social Workers and Miscellaneous staff50 (19.1)0
Housekeeping staff35 (13.4)2 (25)
Security personnel30 (11.4)1 (12.5)
Pharmacists28 (10.7)0
Technicians/Engineers7 (2.6)0

Completed vaccination is defined as those who had received two doses of COVID vaccine before the start of the study.

Table 3

Willingness to vaccinate their children.

CharacteristicsRESPONSESP value*
Yes if rolls out N (%)NoN (%)Not sureN (%)Total
Gender
Male107 (46.7)15 (44.1)3(50)1250.958
Female122 (53.3)19 (55.1)3(50)144
ResidencePuducherry224 (97.8)32 (94.1)62620.414
Others5 (2.2)2 (5.9)07
Doctors/PhD Scholars31 (13.5)5 (14.7)1(16.6)370.000
Nursing officers74 (32.3)3 (8.8)2( 33.3)79
Medical Social Workers & Miscellaneous staff50 (21.8)0050
Housekeeping staff24 (10.4)12 (35.3)1(16.6)37
Security Personnel17 (7.4)12 (35.3)2(33.3)31
Pharmacists28 (12.2)0028
Technicians/Engineers5 (2.1)2 (5.9)07

Pearson‘s chi-square test.

Table 4

Reasons for not willing to vaccinate their children when vaccine is made available.

S. NoReasons for not willing to vaccinate their childrenNumbers N (%) N = 34
1Worried about adverse effects12 (4.5)
2Was advised against it2 (0.7)
3Illness not severe in children16 (6)
4Underlying comorbidities preclude vaccination2 (0.7)
5Adverse events following immunisation in the past2 (0.7)
6Others (waiting for pan coronavirus vaccine, research lacuna, combined)3 (1.1)

Multiple responses possible for each participant.

Sociodemographic characteristics of the Health care-worker parents in a tertiary care institute, Puducherry, India, 2022. COVID Vaccination status of study participants. Completed vaccination is defined as those who had received two doses of COVID vaccine before the start of the study. Willingness to vaccinate their children. Pearson‘s chi-square test. Reasons for not willing to vaccinate their children when vaccine is made available. Multiple responses possible for each participant. Majority of the infected had mild symptoms and were under home quarantine. Hospitalization and or intensive care unit stay was needed for two nurses and one housekeeping staff (Table 5 ). While analysing the responses to the MOVHS questionnaire (appendix 1), it was seen that the responses were predominantly positive for all the questions among doctors, nurses, MSWs, pharmacists, technicians and security whereas it was predominantly negative for housekeeping staff (Table 6 ).
Table 5

Morbidity pattern of participants during their COVID-19 infection.

OccupationHome QuarantineHospitalization/ ICU CareNot InfectedTotal
Doctors/PhD Scholars21016 (43.2)37
Nursing officers25252 (65.8)79
Medical Social Workers & miscellaneous staff11039 (78)50
Housekeeping staff8129(76.3)38
Security Personnel7024 (77.4)31
Pharmacists7021 (75)28
Technicians/Engineers007 (1 0 0)7
Table 6

Occupation wise response of the participants to the Modified Oxford VHS Questionnaire.

S.No of question-naire itemsOccupationResponses to the questionnaire items
P value*
123456
1Doctors/PhD Scholars (37)201101500.00
Nursing officers(79)45303100
Medical Social Workers& Miscellaneous staff (50)18320000
Housekeeping staff (37)4426210
Security Personnel(31)11154010
Pharmacists(28)13150000
Technicians/Engineers(7)131020
2Doctors/PhD Scholars (37)25551100.00
Nursing officers(79)44332000
Medical Social Workers& Miscellaneous staff (50)29210000
Housekeeping staff (37)30191500
Security Personnel(31)13143010
Pharmacists(28)13150000
Technicians/Engineers(7)411100
3Doctors/PhD Scholars (37)161621200.00
Nursing officers(79)27447010
Medical Social Workers& Miscellaneous staff (50)12380000
Housekeeping staff (37)24181201
Security Personnel(31)7203001
Pharmacists(28)6184000
Technicians/Engineers(7)320110
4Doctors/PhD Scholars (37)171071200.00
Nursing officers(79)25521100
Medical Social Workers& Miscellaneous staff (50)16340000
Housekeeping staff (37)24151600
Security Personnel(31)7212100
Pharmacists(28)4240000
Technicians/Engineers(7)132100
5Doctors/PhD Scholars (37)20924200.00
Nursing officers(79)24522100
Medical Social Workers& Miscellaneous staff (50)23270000
Housekeeping staff (37)6617800
Security Personnel(31)12171100
Pharmacists(28)15130000
Technicians/Engineers(7)310210
6Doctors/PhD Scholars (37)151614100.00
Nursing officers(79)28500100
Medical Social Workers& Miscellaneous staff (50)11380100
Housekeeping staff (37)21315700
Security Personnel(31)14141200
Pharmacists(28)14110030
Technicians/Engineers(7)311200
7Doctors/PhD Scholars (37)181340100.00
Nursing officers(79)38365000
Medical Social Workers& Miscellaneous staff (50)24260000
Housekeeping staff (37)6915610
Security Personnel(31)11154010
Pharmacists(28)11143000
Technicians/Engineers(7)222100

* P value by Pearson‘s Chi square test. For the list of questions and key to the scale response code refer to supplementary files

Morbidity pattern of participants during their COVID-19 infection. Occupation wise response of the participants to the Modified Oxford VHS Questionnaire. * P value by Pearson‘s Chi square test. For the list of questions and key to the scale response code refer to supplementary files While analysing the responses to the VHS questionnaire, a tendency towards positive response was seen predominantly in all sections of HCWPs for statements 1–3. For statement 4, a tendency towards positive response was predominantly seen among all sections of HCWPs except nurses and MSWs and miscellaneous staff group. For statement 5, majority of HCWPs except doctors displayed a predominant trend towards disagreement. For statement 6 there was predominantly neutral response for majority of HCWPs except for doctors and nurses who displayed varying degrees of neutrality and agreement. For statements 7–9, a tendency towards agreement was seen predominantly in all sections of HCWPs. For statement 10, neutral responses or a trend towards agreement was seen predominantly in all classes of HCWPs except in housekeeping staff in whom the responses were predominantly towards disagreement (Table 7 ). On analysing the relationship between positive responses to MOVHS questionnaire and the likelihood of self-vaccination and vaccinating their children, it was seen that there was a significant association between proportion of HCWPs with positive response and self-vaccination and vaccinating their children for all classes with the exception of housekeeping staff in whom although the proportion with positive responses is low, the proportion of self-vaccination and vaccinating their children was high (Table 8 ).
Table 7

Occupation wise response of the participants to the VHS LIKERT Scale questions.

S.No of question-naire itemsOccupationResponse to the LIKERT scale questions
P value*
12345
1Doctors/PhD Scholars (37)1122310.223
Nursing officers(79)0151063
Medical Social Workers& Miscellaneous staff (50)001346
Housekeeping staff (37)011035
Security Personnel(31)211225
Pharmacists(28)003025
Technicians/Engineers(7)00106
2Doctors/PhD Scholars (37)0068230.101
Nursing officers(79)0141559
Medical Social Workers& Miscellaneous staff (50)003839
Housekeeping staff (37)010630
Security Personnel(31)213223
Pharmacists(28)002323
Technicians/Engineers(7)00106
3Doctors/PhD Scholars (37)1027270.044
Nursing officers(79)0151360
Medical Social Workers& Miscellaneous staff (50)0001535
Housekeeping staff (37)0011224
Security Personnel(31)3111016
Pharmacists(28)000622
Technicians/Engineers(7)10015
4Doctors/PhD Scholars (37)01210240.001
Nursing officers(79)00243223
Medical Social Workers& Miscellaneous staff (50)00142115
Housekeeping staff (37)0121816
Security Personnel(31)0171112
Pharmacists(28)0001216
Technicians/Engineers(7)00205
5Doctors/PhD Scholars (37)11616310.001
Nursing officers(79)12412420
Medical Social Workers& Miscellaneous staff (50)1429601
Housekeeping staff (37)424801
Security Personnel(31)620221
Pharmacists(28)217810
Technicians/Engineers(7)41200
6Doctors/PhD Scholars (37)31118140.000
Nursing officers(79)07311229
Medical Social Workers& Miscellaneous staff (50)063761
Housekeeping staff (37)1101934
Security Personnel(31)072013
Pharmacists(28)041428
Technicians/Engineers(7)10312
7Doctors/PhD Scholars (37)10517140.007
Nursing officers(79)1112848
Medical Social Workers& Miscellaneous staff (50)0022919
Housekeeping staff (37)1101619
Security Personnel(31)015205
Pharmacists(28)0011215
Technicians/Engineers(7)00016
8Doctors/PhD Scholars (37)00110260.74
Nursing officers(79)0012355
Medical Social Workers& Miscellaneous staff (50)0001238
Housekeeping staff (37)101728
Security Personnel(31)111919
Pharmacists(28)000919
Technicians/Engineers(7)00016
9Doctors/PhD Scholars (37)299980.000
Nursing officers(79)41672824
Medical Social Workers& Miscellaneous staff (50)0252518
Housekeeping staff (37)1121518
Security Personnel(31)115195
Pharmacists(28)0701011
Technicians/Engineers(7)20131
10Doctors/PhD Scholars (37)8663140.000
Nursing officers(79)63224116
Medical Social Workers& Miscellaneous staff (50)4153010
Housekeeping staff (37)1512433
Security Personnel(31)1111603
Pharmacists(28)581230
Technicians/Engineers(7)23110

* P value by Pearson‘s Chi square test. For the list of questions and key to the scale response code refer to supplementary files.

Table 8

Comparison of positive response to NHS questionnaire and vaccination status of self and children occupation wise.

S. NoOccupationPositive Response N (%)Self-VaccinationN (%)Vaccination of childrenN (%)P Value
1Doctors/PhD Scholars (37)30 (13.7)37 (14.1)31 (13.5)0.001241Pearson R −0.9464
2Nursing officers (79)75 (34.2)74 (28.3)74 (32.3)
3Medical Social Worker & miscellaneous staff (50)50 (22.8)50 (19.1)50 (21.8)
4Housekeeping Staff (37)7 (3.19)35 (13.4)24 (10.4)
5Security Personnel (31)27 (12.3)30 (11.4)17 (7.4)
6Pharmacists (28)26 (11.8)28 (10)28 (12.2)
7Technicians/Engineers (7)4 (1.8)7 (2.6)5 (2.1)
Total219261229
Occupation wise response of the participants to the VHS LIKERT Scale questions. * P value by Pearson‘s Chi square test. For the list of questions and key to the scale response code refer to supplementary files. Comparison of positive response to NHS questionnaire and vaccination status of self and children occupation wise.

Discussion:

In our study, majority (97 %) of HCWPs were fully vaccinated. Recent covid illness, fear of adverse effects and recent miscarriage were cited as reasons for not getting vaccinated. Majority of the HCWPs were willing to vaccinate the children once it is made available. Mild presentation of COVID-19 in children and adverse effects were the reasons for unwillingness among parents regarding vaccination of their children. In the United States (U.S), 15 % of the health care workers were hesitant to receive COVID-19 vaccines compared to only 3 % in our study. [14] In another study done among medical students in Ethiopia, about 85 % of the participants responded favourably to questions related to covid-19 vaccination which is also similar to our study. [15] Our finding is also similar to the COVID-19 vaccine hesitancy survey report among general public from seven Caribbean countries published by the United Nation‘s Children‘s education fund (UNICEF) in 2021. According to the UNICEF report, 62 % of their study population indicated that they had been vaccinated and the majority also indicated that they would get their children vaccinated at secondary care or tertiary care institutions. [16]. In an Indian study conducted in early 2021 among 1638 participants from 27 states/union territories who took the survey, the majority of the participants being 18–30 years old (52 %), living in urban areas (69 %), with college education (81 %), without a history of COVID-19 infection (92 %). More than a fifth were either unaware of the vaccines (20.63 %) or were not sure if they will get the vaccine (27 %), and 10 % indicated that they will refuse to obtain the vaccine even if it was made available. Almost 70 % of the population had concerns regarding the vaccines. Statistically significant differences (p less than 0.01) in awareness about vaccine and acceptability were observed based on age, educational qualifications, and employment status. [17] Our findings are strikingly different from the above study as our study was done among HCWPs and almost every-one was aware of the importance of COVID-19 vaccines and the number of persons who had concerns with the vaccine was very negligible. When analysing the reasons for not vaccinating, only three respondents indicated a reason each for not vaccinating themselves out of which one person was apprehensive of adverse effects of vaccination. Among the responses regarding vaccination of children although many parents felt COVID-19 is a mild illness in children and therefore do not require vaccination, the second most common cause was fear of adverse effects in their children. Similarly, another study from Turkey too reported that fear of adverse effects of vaccination is a significant driver of vaccine hesitancy. [18]. With reference to vaccinating their children, although the majority of HCWPs had a positive mind set about vaccinating their children, variations in opinions existed among different class of workers; a higher proportion of security personnel and housekeeping staff opined that they would not vaccinate their children compared to the rest of other professions indicating that differences in socio-economic and educational status might make people behave differently based on inadequate information and biased perceptions. Such differences have also been implicated as one of the reason for poor vaccine coverage in another Indian study which looked at the vaccination rates after the second wave. [19]. Our study attempted to look at vaccine hesitancy among health care worker parents and their perceptions about vaccinating their children against COVID-19. The major strength of our study is that it is one of the few studies carried out in a high risk population of health care workers who are parents. The limitations being a single centre study and inability to collect responses from all participants, the reasons for not vaccinating themselves and under representation of nursing officers, technicians and engineers and over representation of medical social workers and miscellaneous staff and pharmacists working at our institute. Although an attempt was made to sample all health care workers based on the proportion of their composition, we were not able to recruit the planned number of participants under each category. There may be a component of recall bias affecting the validity of our study result as information concerning vaccination was obtained by asking the participants for relevant details. As the study was descriptive in nature we did not check for any interaction and also did not do any analysis for confounding. To conclude we find that vaccine hesitancy in our population of health care worker parents were much less compared to other studies. Most HCWPs responded positively about vaccination of self as well as their children. Among HCWPs certain groups had perceptual differences regarding vaccinating themselves and their children. Further studies are needed to analyse why such differences exist and how to mitigate them.

Contributions

All authors were involved in conceptualization and designing the methodology of the study. PS carried out the study under guidance and supervision from VC, DG, and PC. PS and VC were involved in data visualization and data analysis. PC was involved in data analysis and contributed to the intellectual content of the manuscript. All authors were involved in reviewing of literature and drafting of the manuscript. All authors have seen and approved the final draft.

Funding

Nil.

Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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