Literature DB >> 3606069

In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer.

K V Rolston, B LeBlanc, D H Ho, G P Bodey.   

Abstract

The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients with cancer. Paldimycin had lower MICs for 90% of isolates than vancomycin did against most isolates tested. Its activity, however, was medium and pH dependent, being greatest in Nutrient broth at a pH of 6.8.

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Year:  1987        PMID： 3606069      PMCID： PMC174800          DOI： 10.1128/AAC.31.4.650

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  Simplified scheme for routine identification of human Staphylococcus species.

Authors:  W E Kloos; K H Schleifer
Journal:  J Clin Microbiol       Date:  1975-01       Impact factor: 5.948

2.  Neutropenia, fever, and infection.

Authors:  A E Brown
Journal:  Am J Med       Date:  1984-03       Impact factor: 4.965

3.  Empiric use of vancomycin during prolonged treatment-induced granulocytopenia. Randomized, double-blind, placebo-controlled clinical trial in patients with acute leukemia.

Authors:  J E Karp; J D Dick; C Angelopulos; P Charache; L Green; P J Burke; R Saral
Journal:  Am J Med       Date:  1986-08       Impact factor: 4.965

4.  Identification of Staphylococcus species with the API STAPH-IDENT system.

Authors:  W E Kloos; J F Wolfshohl
Journal:  J Clin Microbiol       Date:  1982-09       Impact factor: 5.948
  4 in total
  3 in total

1.  Comparative in vitro activity of the two new 4-quinolones S-25930 and S-25932 against gram-positive bacteria isolated from cancer patients.

Authors:  K V Rolston; D H Ho; B LeBlanc; G P Bodey
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-10       Impact factor: 3.267

Review 2.  World-wide development of antibiotic resistance in pneumococci.

Authors:  P C Appelbaum
Journal:  Eur J Clin Microbiol       Date:  1987-08       Impact factor: 3.267

3.  In vitro activities of daptomycin (LY146032) and paldimycin (U-70,138F) against anaerobic gram-positive bacteria.

Authors:  A W Chow; N Cheng
Journal:  Antimicrob Agents Chemother       Date:  1988-05       Impact factor: 5.191
  3 in total

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