Rodrigo Casanueva1, Fernando López2,3,4,5, Patricia García-Cabo1,6,7,8, César Álvarez-Marcos1,6,7,8, José Luis Llorente1,6,7,8, Juan Pablo Rodrigo1,6,7,8. 1. Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, Avenida de Roma, s/n, 33011, Oviedo, Spain. 2. Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, Avenida de Roma, s/n, 33011, Oviedo, Spain. flopez_1981@yahoo.es. 3. Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain. flopez_1981@yahoo.es. 4. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), ISCIII, Madrid, Spain. flopez_1981@yahoo.es. 5. Instituto Universitario de Oncología del Principado de Asturias, University of Oviedo, Oviedo, Spain. flopez_1981@yahoo.es. 6. Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain. 7. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), ISCIII, Madrid, Spain. 8. Instituto Universitario de Oncología del Principado de Asturias, University of Oviedo, Oviedo, Spain.
Abstract
BACKGROUND: Surgical resection or radiotherapy (RT) are standard approaches for early-staged hypopharyngeal squamous cell carcinoma (HPSCC). Transoral laser microsurgery (TOLMS) seems to provide good oncological and functional results with few local complications. The aim of our study was to analyze the outcomes of TOLMS, with or without neck dissection or RT, in the treatment of HPSCC in a tertiary referral center. METHODS: A retrospective study was conducted in patients with early T-category (T1-T2) HPSCC treated by TOLMS. RESULTS: A total of 34 patients were included in the study. The series includes 17 (50%) T1 and 17 (50%) T2 classified tumors. The 5-year overall survival and disease-specific survival rates were 51% and 66%, respectively, with a 5-year local control rate of 92%. All patients reassumed oral diet and none of them had a tracheostomy at the end of the follow-up. CONCLUSIONS: TOLMS offers an effective treatment option in terms of oncologic control and function preservation in locally circumscribed HPSCC.
BACKGROUND: Surgical resection or radiotherapy (RT) are standard approaches for early-staged hypopharyngeal squamous cell carcinoma (HPSCC). Transoral laser microsurgery (TOLMS) seems to provide good oncological and functional results with few local complications. The aim of our study was to analyze the outcomes of TOLMS, with or without neck dissection or RT, in the treatment of HPSCC in a tertiary referral center. METHODS: A retrospective study was conducted in patients with early T-category (T1-T2) HPSCC treated by TOLMS. RESULTS: A total of 34 patients were included in the study. The series includes 17 (50%) T1 and 17 (50%) T2 classified tumors. The 5-year overall survival and disease-specific survival rates were 51% and 66%, respectively, with a 5-year local control rate of 92%. All patients reassumed oral diet and none of them had a tracheostomy at the end of the follow-up. CONCLUSIONS: TOLMS offers an effective treatment option in terms of oncologic control and function preservation in locally circumscribed HPSCC.
Authors: Bernhard G Weiss; Friedrich Ihler; Hendrik A Wolff; Simon Schneider; Martin Canis; Wolfgang Steiner; Christian Welz Journal: Head Neck Date: 2017-05-05 Impact factor: 3.147
Authors: Robert P Takes; Primož Strojan; Carl E Silver; Patrick J Bradley; Missak Haigentz; Gregory T Wolf; Ashok R Shaha; Dana M Hartl; Jan Olofsson; Johannes A Langendijk; Alessandra Rinaldo; Alfio Ferlito Journal: Head Neck Date: 2010-11-10 Impact factor: 3.147