Literature DB >> 36053248

Lead Optimization of Nerve-Specific Fluorophores for Image-Guided Nerve Sparing Surgical Procedures.

Connor W Barth1, Lei G Wang2, Antonio Montano2, Alexander L Antaris3, Alwin Klaassen3, Jonathan Sorger3, Darcy A Kerr4,5, Eric R Henderson6, Adam W G Alani2,7, Summer L Gibbs2,8.   

Abstract

Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.

Entities:  

Year:  2021        PMID： 36053248      PMCID： PMC9431774          DOI： 10.1364/OMP.2021.OW3E.3

Source DB:  PubMed          Journal:  Opt Mol Probes Imaging Drug Deliv


  23 in total

1.  Lighting up the senses: FM1-43 loading of sensory cells through nonselective ion channels.

Authors:  Jason R Meyers; Richard B MacDonald; Anne Duggan; David Lenzi; David G Standaert; Jeffrey T Corwin; David P Corey
Journal:  J Neurosci       Date:  2003-05-15       Impact factor: 6.167

2.  In situ fluorescence imaging of myelination.

Authors:  Changning Wang; Daniela C Popescu; Chunying Wu; Junqing Zhu; Wendy Macklin; Yanming Wang
Journal:  J Histochem Cytochem       Date:  2010-03-30       Impact factor: 2.479

3.  National Hospital Discharge Survey: 2007 summary.

Authors:  Margaret Jean Hall; Carol J DeFrances; Sonja N Williams; Aleksandr Golosinskiy; Alexander Schwartzman
Journal:  Natl Health Stat Report       Date:  2010-10-26

4.  Imaging of CNS myelin by positron-emission tomography.

Authors:  Bruno Stankoff; Yanming Wang; Michel Bottlaender; Marie-Stephane Aigrot; Frederic Dolle; Chunying Wu; Douglas Feinstein; Guo-Feng Huang; Frank Semah; Chester A Mathis; William Klunk; Robert M Gould; Catherine Lubetzki; Bernard Zalc
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-05       Impact factor: 11.205

5.  Molecular imaging agents specific for the annulus fibrosus of the intervertebral disk.

Authors:  Summer L Gibbs-Strauss; Carrie Vooght; Kenneth M Fish; Khaled A Nasr; Tiberiu M Siclovan; Nicole E Barnhardt; Cristina A Tan Hehir; John V Frangioni
Journal:  Mol Imaging       Date:  2010-06       Impact factor: 4.488

6.  Longitudinal near-infrared imaging of myelination.

Authors:  Changning Wang; Chunying Wu; Daniela C Popescu; Junqing Zhu; Wendy B Macklin; Robert H Miller; Yanming Wang
Journal:  J Neurosci       Date:  2011-02-16       Impact factor: 6.167

7.  Prototype nerve-specific near-infrared fluorophores.

Authors:  Min Ho Park; Hoon Hyun; Yoshitomo Ashitate; Hideyuki Wada; GwangLi Park; Jeong Heon Lee; Costyl Njiojob; Maged Henary; John V Frangioni; Hak Soo Choi
Journal:  Theranostics       Date:  2014-06-07       Impact factor: 11.556

8.  Direct Administration of Nerve-Specific Contrast to Improve Nerve Sparing Radical Prostatectomy.

Authors:  Connor W Barth; Summer L Gibbs
Journal:  Theranostics       Date:  2017-01-07       Impact factor: 11.556

9.  Nerve-targeted probes for fluorescence-guided intraoperative imaging.

Authors:  Dina V Hingorani; Michael A Whitney; Beth Friedman; Joong-Keun Kwon; Jessica L Crisp; Qing Xiong; Larry Gross; Christopher J Kane; Roger Y Tsien; Quyen T Nguyen
Journal:  Theranostics       Date:  2018-07-30       Impact factor: 11.556

10.  Structure-activity relationship of nerve-highlighting fluorophores.

Authors:  Summer L Gibbs; Yang Xie; Haley L Goodwill; Khaled A Nasr; Yoshitomo Ashitate; Victoria J Madigan; Tiberiu M Siclovan; Maria Zavodszky; Cristina A Tan Hehir; John V Frangioni
Journal:  PLoS One       Date:  2013-09-09       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.