| Literature DB >> 3605280 |
L M Hamed, F D Ellis, G Boudreault, F M Wilson, E M Helveston.
Abstract
Presumed accidental corneal exposure to Hibiclens (chlorhexidine 4% and detergent) in two patients resulted in severe and permanent corneal opacification. We investigated the corneal toxicity of Hibiclens by gross, biomicroscopic, and histopathologic studies of rabbit eyes exposed to Hibiclens for varying time intervals ranging from five to 15 minutes. Severe, irreversible, and progressive corneal damage resulted in all eyes studied.Entities:
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Year: 1987 PMID： 3605280 DOI： 10.1016/0002-9394(87)90292-3
Source DB: PubMed Journal: Am J Ophthalmol ISSN： 0002-9394 Impact factor: 5.258