Literature DB >> 36046330

Post-COVID Mucormycosis of Mandible: A Conundrum of Management.

Ashish Gopal1, Raman Sharma1, Sakshi Negi1, Ishwar Singh1.   

Abstract

Mucormycosis is an acute invasive infection of paranasal sinuses, with the propensity to spread from paranasal sinuses to intra-orbital and cranium. It is usually associated with immunocompromised states like diabetes mellitus, hematological malignancies, long-term steroids, neutropenia, and other multiple systemic disorders. Mucormycosis cases had been upsurging following COVID-19 infection. Due to the rampant use of steroids, pulmonary involvement secondary to cytokine upsurge, and deranged blood sugar levels in diabetic patients, mucormycosis of paranasal sinuses and neighboring anatomical structures has occurred at an unprecedented rate. The isolated involvement of the mandible is infrequent, and very few cases have been reported in the literature. We report one such case of post-COVID-19 isolated mandibular mucormycosis and its management. Generally, surgical excision and reconstruction of defect followed by a course of broad-spectrum antifungals are described as the appropriate line of management for this condition. However, on the contrary, we followed conservative management as the sole treatment because of the various challenges concerning undesirable postoperative consequences and reducing morbidity for the patient.
Copyright © 2022, Gopal et al.

Entities:  

Keywords:  covid 19; fungal; mandible; mandibulectomy; mucormycosis

Year:  2022        PMID: 36046330      PMCID: PMC9418873          DOI: 10.7759/cureus.27382

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  16 in total

1.  Study on invasive aspergillosis using galactomannan enzyme immunoassay and determining antifungal drug susceptibility among hospitalized patients with hematologic malignancies or candidates for organ transplantation.

Authors:  Pegah Ardi; Roshanak Daie-Ghazvini; Seyed Jamal Hashemi; Mohammad Reza Salehi; Heidar Bakhshi; Zahra Rafat; Mahdi Zareei; Muhammad Getso; Solmaz Basiri; Hasti Kamali Sarwestani; Zeinab Borjian Boroujeini; Kazem Ahmadikia
Journal:  Microb Pathog       Date:  2020-07-12       Impact factor: 3.738

2.  Mucormycosis of the mandible.

Authors:  O E Brown; R Finn
Journal:  J Oral Maxillofac Surg       Date:  1986-02       Impact factor: 1.895

3.  Severe soft tissue infection of the face and neck: a classification.

Authors:  M E Klabacha; J A Stankiewicz; S E Clift
Journal:  Laryngoscope       Date:  1982-10       Impact factor: 3.325

Review 4.  How I treat mucormycosis.

Authors:  Dimitrios P Kontoyiannis; Russell E Lewis
Journal:  Blood       Date:  2011-05-26       Impact factor: 22.113

5.  Quality of life after mandibulectomy: the impact of the resected subsite.

Authors:  A Warshavsky; D M Fliss; G Frenkel; A Kupershmidt; N Moav; R Rosen; M Sechter; U Shapira; S Abu-Ghanem; M Yehuda; A Zaretski; R Yanko-Arzi; V Reiser; G Horowitz
Journal:  Int J Oral Maxillofac Surg       Date:  2019-03-11       Impact factor: 2.789

6.  Infectious facial and nasal cutaneous necrosis: evaluation and diagnosis.

Authors:  C F Koopmann; S W Coulthard
Journal:  Laryngoscope       Date:  1982-10       Impact factor: 3.325

7.  Mucor menace in an immunocompetent young male after dental manipulation.

Authors:  Nitin Gupta; Rajeev Kumar; Manish Soneja; Gagandeep Singh; Wasim Khot; Sundeep Malla; Immaculata Xess
Journal:  J Family Med Prim Care       Date:  2019-02

8.  SARS-CoV-2, Uncontrolled Diabetes and Corticosteroids-An Unholy Trinity in Invasive Fungal Infections of the Maxillofacial Region? A Retrospective, Multi-centric Analysis.

Authors:  Aditya Moorthy; Rohith Gaikwad; Shreya Krishna; Raghuraj Hegde; K K Tripathi; Preeti G Kale; P Subramanya Rao; Deepak Haldipur; Krishnamurthy Bonanthaya
Journal:  J Maxillofac Oral Surg       Date:  2021-03-06

9.  Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

Authors:  Jonas Schulte-Schrepping; Nico Reusch; Daniela Paclik; Kevin Baßler; Stephan Schlickeiser; Bowen Zhang; Benjamin Krämer; Tobias Krammer; Sophia Brumhard; Lorenzo Bonaguro; Elena De Domenico; Daniel Wendisch; Martin Grasshoff; Theodore S Kapellos; Michael Beckstette; Tal Pecht; Adem Saglam; Oliver Dietrich; Henrik E Mei; Axel R Schulz; Claudia Conrad; Désirée Kunkel; Ehsan Vafadarnejad; Cheng-Jian Xu; Arik Horne; Miriam Herbert; Anna Drews; Charlotte Thibeault; Moritz Pfeiffer; Stefan Hippenstiel; Andreas Hocke; Holger Müller-Redetzky; Katrin-Moira Heim; Felix Machleidt; Alexander Uhrig; Laure Bosquillon de Jarcy; Linda Jürgens; Miriam Stegemann; Christoph R Glösenkamp; Hans-Dieter Volk; Christine Goffinet; Markus Landthaler; Emanuel Wyler; Philipp Georg; Maria Schneider; Chantip Dang-Heine; Nick Neuwinger; Kai Kappert; Rudolf Tauber; Victor Corman; Jan Raabe; Kim Melanie Kaiser; Michael To Vinh; Gereon Rieke; Christian Meisel; Thomas Ulas; Matthias Becker; Robert Geffers; Martin Witzenrath; Christian Drosten; Norbert Suttorp; Christof von Kalle; Florian Kurth; Kristian Händler; Joachim L Schultze; Anna C Aschenbrenner; Yang Li; Jacob Nattermann; Birgit Sawitzki; Antoine-Emmanuel Saliba; Leif Erik Sander
Journal:  Cell       Date:  2020-08-05       Impact factor: 41.582

10.  The emergence of post-COVID-19 mucormycosis in India: Can we prevent it?

Authors:  Amod Gupta; Aman Sharma; Arunaloke Chakrabarti
Journal:  Indian J Ophthalmol       Date:  2021-07       Impact factor: 1.848

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