Literature DB >> 36036135

Recent research on the association between signal transducer and activator of transcription 5 and childhood acute lymphoblastic leukemia.

Yi-Fei Duan1, Fei-Qiu Wen1.   

Abstract

Signal transducer and activator of transcription 5 (STAT5) can be involved in the processes such as cell proliferation, differentiation, apoptosis, and hematopoiesis, and its dysregulation is closely associated with the development and progression of malignant tumors including leukemia and may affect the treatment outcome and prognosis of pediatric patients. Identification of STAT5 can facilitate targeted therapy to improve the response rate of children with acute lymphoblastic leukemia. This article reviews the impact of STAT5 on the development/progression, targeted therapy strategies and the prognosis of childhood acute lymphoblastic leukemia.

Entities:  

Keywords:  Acute lymphoblastic leukemia; Child; Signal transducer and activator of transcription 5; Signal transduction

Mesh：

Substances：

Year:  2022        PMID： 36036135      PMCID： PMC9425862          DOI： 10.7499/j.issn.1008-8830.2203117

Source DB:  PubMed          Journal:  Zhongguo Dang Dai Er Ke Za Zhi        ISSN： 1008-8830


  44 in total

1.  SnapShot: Jak-STAT Signaling II.

Authors:  Alejandro V Villarino; Massimo Gadina; John J O'Shea; Yuka Kanno
Journal:  Cell       Date:  2020-06-25       Impact factor: 41.582

2.  [Clinical Biological Characteristics and Prognostic Factors of Children with Ph+ALL].

Authors:  Zhou-Yang Liu; Yuan Sun
Journal:  Zhongguo Shi Yan Xue Ye Xue Za Zhi       Date:  2019-12

3.  Childhood cancer incidence and survival in Japan and England: A population-based study (1993-2010).

Authors:  Kayo Nakata; Yuri Ito; Winnie Magadi; Audrey Bonaventure; Charles A Stiller; Kota Katanoda; Tomohiro Matsuda; Isao Miyashiro; Kathy Pritchard-Jones; Bernard Rachet
Journal:  Cancer Sci       Date:  2017-12-26       Impact factor: 6.716

4.  Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.

Authors:  Casey D S Katerndahl; Lynn M Heltemes-Harris; Mark J L Willette; Christine M Henzler; Seth Frietze; Rendong Yang; Hilde Schjerven; Kevin A T Silverstein; Laura B Ramsey; Gregory Hubbard; Andrew D Wells; Roland P Kuiper; Blanca Scheijen; Frank N van Leeuwen; Markus Müschen; Steven M Kornblau; Michael A Farrar
Journal:  Nat Immunol       Date:  2017-04-03       Impact factor: 25.606

5.  Telomerase (hTERT) Overexpression Reveals a Promising Prognostic Biomarker and Therapeutical Target in Different Clinical Subtypes of Pediatric Acute Lymphoblastic Leukaemia.

Authors:  Beatriz Maria Dias Nogueira; Laudreísa da Costa Pantoja; Emerson Lucena da Silva; Fernando Augusto Rodrigues Mello Júnior; Eliel Barbosa Teixeira; Alayde Vieira Wanderley; Jersey Heitor da Silva Maués; Manoel Odorico de Moraes Filho; Maria Elisabete Amaral de Moraes; Raquel Carvalho Montenegro; André Salim Khayat; Caroline Aquino Moreira-Nunes
Journal:  Genes (Basel)       Date:  2021-10-17       Impact factor: 4.096

6.  Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity.

Authors:  Zhi-Chun Ding; Huidong Shi; Nada S Aboelella; Kateryna Fesenkova; Eun-Jeong Park; Zhuoqi Liu; Lirong Pei; Jiaqi Li; Richard A McIndoe; Hongyan Xu; Gary A Piazza; Bruce R Blazar; David H Munn; Gang Zhou
Journal:  Sci Immunol       Date:  2020-10-30

7.  Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.

Authors:  Kerri R Thomas; Eric J Allenspach; Nathan D Camp; Michelle N Wray-Dutra; Socheath Khim; Anna Zielinska-Kwiatkowska; Andrew E Timms; Joseph P Loftus; H Denny Liggitt; Katia Georgopoulos; Sarah K Tasian; Richard G James; David J Rawlings
Journal:  Leukemia       Date:  2021-06-30       Impact factor: 11.528

8.  Therapeutic delivery of siRNA with polymeric carriers to down-regulate STAT5A expression in high-risk B-cell acute lymphoblastic leukemia (B-ALL).

Authors:  Mahsa Mohseni; Cezary Kucharski; Remant Bahadur K C; Mohammad Nasrullah; Xiaoyan Jiang; Hasan Uludağ; Joseph Brandwein
Journal:  PLoS One       Date:  2021-06-22       Impact factor: 3.240

9.  Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.

Authors:  Marlies Vanden Bempt; Sofie Demeyer; Michaël Broux; Jolien De Bie; Simon Bornschein; Nicole Mentens; Roel Vandepoel; Ellen Geerdens; Enrico Radaelli; Beat C Bornhauser; Andreas E Kulozik; Jules P Meijerink; Jean-Pierre Bourquin; Charles E de Bock; Jan Cools
Journal:  Cancer Cell       Date:  2018-08-13       Impact factor: 31.743
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