Literature DB >> 36036039

Ketamine Infusions Administered Solely by Psychiatric Staff.

Muaid Ithman1, Robert Sobule2, Carolyn Kundert3, Austin Campbell4, Elizabeth Ehrhardt5.   

Abstract

Even though intravenous ketamine is not an FDA-approved depression treatment, multiple studies have shown a robust antidepressant effect which has led to an increase in clinical practices implementing its use to manage treatment-resistant depression. Traditionally, this therapy has been provided in both outpatient and inpatient settings, with anesthesia specialists and psychiatrists working collaboratively on most cases. Several studies have been conducted in various psychiatric settings to study the effects of ketamine in depression, mostly in a collaborative manner. Thorough search of the literature found no published reports on the use of ketamine infusions merely for clinical purposes in a psychiatric hospital setting, implemented solely by a psychiatric-based team without collaboration from anesthesia specialists. In an effort to explore the utilization of ketamine infusions, the Missouri University Psychiatric Center (MUPC), an acute mental inpatient facility, formed a ketamine infusion team composed solely of mental health clinicians and staff to investigate the use of ketamine infusions by a psychiatric team. To our knowledge, this is the first-time ketamine infusions have been administered by a clinically based psychiatric team in a psychiatric hospital. The MUPC ketamine team has proved that ketamine infusions may provide a unique intervention safely and efficaciously without the need for collaboration with other medical specialties since initiating this pilot program. Copyright 2022 by the Missouri State Medical Association.

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Year:  2022        PMID: 36036039      PMCID: PMC9339397     

Source DB:  PubMed          Journal:  Mo Med        ISSN: 0026-6620


  7 in total

1.  Ketamine: a familiar drug we trust.

Authors:  Jaume Canet; Jorge Castillo
Journal:  Anesthesiology       Date:  2012-01       Impact factor: 7.892

2.  Therapeutic Mechanisms of Ketamine.

Authors:  Slobodan Mihaljević; Matko Pavlović; Krešimir Reiner; Marko Ćaćić
Journal:  Psychiatr Danub       Date:  2020 Autumn - Winter       Impact factor: 1.063

Review 3.  Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.

Authors:  Panos Zanos; Ruin Moaddel; Patrick J Morris; Lace M Riggs; Jaclyn N Highland; Polymnia Georgiou; Edna F R Pereira; Edson X Albuquerque; Craig J Thomas; Carlos A Zarate; Todd D Gould
Journal:  Pharmacol Rev       Date:  2018-07       Impact factor: 25.468

Review 4.  Ketamine use in current clinical practice.

Authors:  Mei Gao; Damoon Rejaei; Hong Liu
Journal:  Acta Pharmacol Sin       Date:  2016-03-28       Impact factor: 6.150

Review 5.  A historical review of antidepressant effects of ketamine and its enantiomers.

Authors:  Yan Wei; Lijia Chang; Kenji Hashimoto
Journal:  Pharmacol Biochem Behav       Date:  2020-02-05       Impact factor: 3.533

6.  Functional antagonists at the NMDA receptor complex exhibit antidepressant actions.

Authors:  R Trullas; P Skolnick
Journal:  Eur J Pharmacol       Date:  1990-08-21       Impact factor: 4.432

Review 7.  Ketamine administration in depressive disorders: a systematic review and meta-analysis.

Authors:  Guillaume Fond; Anderson Loundou; Corentin Rabu; Alexandra Macgregor; Christophe Lançon; Marie Brittner; Jean-Arthur Micoulaud-Franchi; Raphaelle Richieri; Philippe Courtet; Mocrane Abbar; Matthieu Roger; Marion Leboyer; Laurent Boyer
Journal:  Psychopharmacology (Berl)       Date:  2014-07-20       Impact factor: 4.530

  7 in total

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