Literature DB >> 36032888

Hearing Assessment in Patients of Allergic Rhinitis: A Study on 200 Subjects.

Dimple Sahni1, Peeyush Verma1, Sanjeev Bhagat1, Vishal Sharma1.   

Abstract

Allergic rhinitis (AR) is a type I hypersensitivity reaction of the nasal mucosa, primarily mediated by IgE, with a complex etiology, determined by genetic and environmental interactions. Several mechanisms by which AR affect middle ear and cause conductive hearing loss have been well described. There is paucity of data regarding involvement of inner ear in AR patients leading to sensorineural hearing loss. However, endolymphatic sac and outer hair cells have been hypothesized to be the seat of immunoreactivity. To study the audiological profile in AR and effect of AR on inner ear functions. 100 cases of AR patients (55 males, 45 females, mean age group 21-30 years) and 100 controls (65 males, 35 females, mean age group 41-50 years) were enrolled in study. All underwent thorough clinical ear, nose and throat examination, diagnostic nasal endoscopy and otoendoscopy, followed by audiological assessment including pure tone audiometry, tympanometry and oto-acoustic emission test. Hearing results of both the groups were compared and analysed statistically. Thirty two patients among case group had sensorineural hearing loss, pronounced at 4000 and 8000 Hz frequencies. 18 patients showed conductive hearing loss in the form of type B or type C tympanogram. 32 patients of AR patients showed unusual oto-acoustic emission test. We found higher prevalence of high frequency sensorineural hearing loss in pure tone audiometry and abnormal OAEs in patients having upper airway allergy. The likely seat of damage appears to be the inner ear as evidenced by recordings of OAE in allergic patients. © Association of Otolaryngologists of India 2020.

Entities:  

Keywords:  Allergic rhinitis; Duct; Endolymphatic sac; Oto acoustic emission; Outer hair cells; Sensorineural hearing loss

Year:  2020        PMID: 36032888      PMCID: PMC9411413          DOI: 10.1007/s12070-020-01890-1

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  20 in total

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Authors:  J Bousquet; P Van Cauwenberge; N Khaltaev
Journal:  J Allergy Clin Immunol       Date:  2001-11       Impact factor: 10.793

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Journal:  J Allergy Clin Immunol       Date:  1997-02       Impact factor: 10.793

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Authors:  Satbir Singh; Anu N Nagarkar; Sandeep Bansal; Dharm Vir; Ashok K Gupta
Journal:  J Laryngol Otol       Date:  2011-06-21       Impact factor: 1.469

Review 4.  Treatment update: nonallergic rhinitis.

Authors:  P Lieberman
Journal:  Allergy Asthma Proc       Date:  2001 Jul-Aug       Impact factor: 2.587

Review 5.  Impact of cetirizine on the burden of allergic rhinitis.

Authors:  E O Meltzer; J A Grant
Journal:  Ann Allergy Asthma Immunol       Date:  1999-11       Impact factor: 6.347

6.  Genetic analysis of allergic disease in twins.

Authors:  R J Hopp; A K Bewtra; G D Watt; N M Nair; R G Townley
Journal:  J Allergy Clin Immunol       Date:  1984-02       Impact factor: 10.793

Review 7.  Epidemiologic evidence for asthma and rhinitis comorbidity.

Authors:  B Leynaert; F Neukirch; P Demoly; J Bousquet
Journal:  J Allergy Clin Immunol       Date:  2000-11       Impact factor: 10.793

Review 8.  Genetic susceptibility to atopic dermatitis.

Authors:  Chikako Kiyohara; Keiko Tanaka; Yoshihiro Miyake
Journal:  Allergol Int       Date:  2008-03-01       Impact factor: 5.836

9.  Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003.

Authors:  S G O Johansson; Thomas Bieber; Ronald Dahl; Peter S Friedmann; Bobby Q Lanier; Richard F Lockey; Cassim Motala; Jose A Ortega Martell; Thomas A E Platts-Mills; Johannes Ring; Frank Thien; Paul Van Cauwenberge; Hywel C Williams
Journal:  J Allergy Clin Immunol       Date:  2004-05       Impact factor: 10.793

10.  The asthma and allergic rhinitis link.

Authors:  Anjuli S Nayak
Journal:  Allergy Asthma Proc       Date:  2003 Nov-Dec       Impact factor: 2.587

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