Literature DB >> 3603287

Gallstone disease among black South Africans. A review of the Baragwanath Hospital experience.

D Parekh, H H Lawson, J M Kuyl.   

Abstract

It has been suggested that gallstone disease is rare in Africa. The 118 cholecystectomies for this condition performed at Baragwanath Hospital over the 3-year period 1983-1985 were reviewed; 100 records were available. The male: female ratio was 1:4, the mean age 51 years. Fifty-one per cent of patients presented with acute cholecystitis, 18% with obstructive jaundice, 9% with pancreatitis and only 22% with biliary colic. The incidence of complicated presentation was higher in the over 60-year-old age group (P less than 0.05). The correct diagnosis was made on admission in only 41% of cases. The mean delay in diagnosis was 5 days; however, the delay was 8 days for patients admitted to the medical wards compared with 2 days in the surgical wards (P less than 0.001). Elective operations were performed on 82% of patients and 18% had urgent surgery. The incidence of common bile duct stones was 22%. The overall mortality rate was 10%; however, the mortality rate was 3.2% for the under-60-year-old group compared with 21% for patients 60 years and older (P = 0.006). This series, which is probably the largest reported in black patients, suggests that greater awareness of acute cholecystitis is necessary in the black patient since there is a rising in-hospital incidence.

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Year:  1987        PMID: 3603287

Source DB:  PubMed          Journal:  S Afr Med J


  5 in total

Review 1.  New pathophysiological concepts underlying pathogenesis of pigment gallstones.

Authors:  Libor Vítek; Martin C Carey
Journal:  Clin Res Hepatol Gastroenterol       Date:  2011-10-05       Impact factor: 2.947

2.  Symptomatic gallstones and HIV in black South African women: Changing trends of gallstone disease?

Authors:  Suman Mewa Kinoo; Savania Nagiah; Anil Chuturgoon; Bhugwan Singh
Journal:  South Afr J HIV Med       Date:  2021-03-25       Impact factor: 2.744

3.  Hepatic expression of cholesterol regulating genes favour increased circulating low-density lipoprotein in HIV infected patients with gallstone disease: a preliminary study.

Authors:  Suman Mewa Kinoo; Anil A Chuturgoon; Bugwan Singh; Savania Nagiah
Journal:  BMC Infect Dis       Date:  2021-03-23       Impact factor: 3.090

4.  A middle aged woman presenting with massive empyema of the gallbladder: a case report.

Authors:  Olukayode Adeolu Arowolo; Oladejo Olukayode Lawal; Andrew Akinbolaji Akinkuolie; Adewale Oluseye Adisa
Journal:  Cases J       Date:  2009-07-21

5.  Increases in cholecystectomy for gallstone related disease in South Africa.

Authors:  Zafar Ahmed Khan; Muhammed Uzayr Khan; Martin Brand
Journal:  Sci Rep       Date:  2020-08-11       Impact factor: 4.379

  5 in total

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