Literature DB >> 36032604

Blood Culture Contamination Rate as a Quality Indicator - a Prospective Observational Study.

Rathod Gunvanti1, Jyothi Tadi Lakshmi2, Kaliappan Ariyanachi3, Mallamgunta Saranya4, Sarvam Kamlakar2, Varatharajan Sakthivadivel5, Archana Gaur6, Shalam Shireen Nikhat2, Triveni Sagar7, Kesavulu Chenna7, Meena S Vidya8.   

Abstract

Introduction: Blood culture test is the gold standard test to diagnose bloodstream infections, but contamination is the main problem in this valuable test. False positive results in blood cultures are mainly due to contamination that occurs mostly during pre-analytical procedures like sample collection and sometimes during sample processing. Materials and method:Our prospective observational study was undertaken at St. Theresa Hospital, Hyderabad, India, during January 2020-June 2020. Blood cultures received from inpatient departments (IPD) and outpatient departments (OPD) are included. Sample size: The contamination rate was calculated by dividing the total number of contaminated blood cultures by the total number of cultures multiplied by 100.
Results: Blood culture contamination rate is 2.4%, which is within the limit as per the standard guideline.
Conclusion: Contamination occurred mainly due to improper disinfection of the skin and environmental contamination.

Entities:  

Year:  2022        PMID: 36032604      PMCID: PMC9375895          DOI: 10.26574/maedica.2022.17.2.311

Source DB:  PubMed          Journal:  Maedica (Bucur)        ISSN: 1841-9038


  21 in total

Review 1.  Blood cultures: clinical aspects and controversies.

Authors:  J M Mylotte; A Tayara
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2000-03       Impact factor: 3.267

Review 2.  Multidisciplinary team review of best practices for collection and handling of blood cultures to determine effective interventions for increasing the yield of true-positive bacteremias, reducing contamination, and eliminating false-positive central line-associated bloodstream infections.

Authors:  Robert A Garcia; Eric D Spitzer; Josephine Beaudry; Cindy Beck; Regina Diblasi; Michelle Gilleeny-Blabac; Carol Haugaard; Stacy Heuschneider; Barbara P Kranz; Karen McLean; Katherine L Morales; Susan Owens; Mary E Paciella; Edwin Torregrosa
Journal:  Am J Infect Control       Date:  2015-08-19       Impact factor: 2.918

Review 3.  Updated review of blood culture contamination.

Authors:  Keri K Hall; Jason A Lyman
Journal:  Clin Microbiol Rev       Date:  2006-10       Impact factor: 26.132

4.  Chlorhexidine compared with povidone-iodine as skin preparation before blood culture. A randomized, controlled trial.

Authors:  O Mimoz; A Karim; A Mercat; M Cosseron; B Falissard; F Parker; C Richard; K Samii; P Nordmann
Journal:  Ann Intern Med       Date:  1999-12-07       Impact factor: 25.391

Review 5.  Contaminants in blood cultures: importance, implications, interpretation and prevention.

Authors:  S Dargère; H Cormier; R Verdon
Journal:  Clin Microbiol Infect       Date:  2018-04-03       Impact factor: 8.067

6.  The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults.

Authors:  M P Weinstein; M L Towns; S M Quartey; S Mirrett; L G Reimer; G Parmigiani; L B Reller
Journal:  Clin Infect Dis       Date:  1997-04       Impact factor: 9.079

7.  Molecular analysis of coagulase-negative Staphylococcus isolates from blood cultures: prevalence of genotypic variation and polyclonal bacteremia.

Authors:  M Sharma; K Riederer; L B Johnson; R Khatib
Journal:  Clin Infect Dis       Date:  2001-09-17       Impact factor: 9.079

8.  Clinical and economic impact of contaminated blood cultures within the hospital setting.

Authors:  Y M Alahmadi; M A Aldeyab; J C McElnay; M G Scott; F W Darwish Elhajji; F A Magee; M Dowds; C Edwards; L Fullerton; A Tate; M P Kearney
Journal:  J Hosp Infect       Date:  2011-01-07       Impact factor: 3.926

9.  Effect of iodophor vs iodine tincture skin preparation on blood culture contamination rate.

Authors:  C L Strand; R R Wajsbort; K Sturmann
Journal:  JAMA       Date:  1993-02-24       Impact factor: 56.272

10.  Quality assurance in blood culture: A retrospective study of blood culture contamination rate in a tertiary hospital in Nigeria.

Authors:  Iregbu Kenneth Chukwuemeka; Yakubu Samuel
Journal:  Niger Med J       Date:  2014-05
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