Literature DB >> 36031764

New sedatives and analgesic drugs for gastrointestinal endoscopic procedures.

Jae Min Lee1, Yehyun Park2, Jin Myung Park3, Hong Jun Park4, Jun Yong Bae5, Seung Young Seo6, Jee Hyun Lee7, Hyung Ku Chon8, Jun-Won Chung9, Hyun Ho Choi10, Jun Kyu Lee11, Byung-Wook Kim12.   

Abstract

Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addition, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and propofol are the most commonly used drugs in sedative endoscopy. In recent years, the need to ascertain the safety and effectiveness of sedation has increased in practice. Therefore, new sedatives and analgesic drugs for optimal sedative endoscopy, have recently emerged. This article reviews the characteristics of sedatives and analgesics, and describes their clinical use in gastrointestinal endoscopy.

Entities:  

Keywords:  Analgesics; Conscious sedation; Endoscopy; Hypnotics and sedatives

Year:  2022        PMID: 36031764      PMCID: PMC9539299          DOI: 10.5946/ce.2021.283

Source DB:  PubMed          Journal:  Clin Endosc        ISSN: 2234-2400


  37 in total

Review 1.  Guidelines for conscious sedation and monitoring during gastrointestinal endoscopy.

Authors:  J Patrick Waring; Todd H Baron; William K Hirota; Jay L Goldstein; Brian C Jacobson; Jonathan A Leighton; J Shawn Mallery; Douglas O Faigel
Journal:  Gastrointest Endosc       Date:  2003-09       Impact factor: 9.427

2.  A Phase IIa, randomized, double-blind study of remimazolam (CNS 7056) versus midazolam for sedation in upper gastrointestinal endoscopy.

Authors:  Keith M Borkett; Dennis S Riff; Howard I Schwartz; Peter J Winkle; Daniel J Pambianco; James P Lees; Karin Wilhelm-Ogunbiyi
Journal:  Anesth Analg       Date:  2015-04       Impact factor: 5.108

3.  Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole: a pharmacodynamic and kinetic study in healthy volunteers.

Authors:  H Scheinin; R Aantaa; M Anttila; P Hakola; A Helminen; S Karhuvaara
Journal:  Anesthesiology       Date:  1998-09       Impact factor: 7.892

4.  A randomized, controlled, double-blind trial of patient-controlled sedation with propofol/remifentanil versus midazolam/fentanyl for colonoscopy.

Authors:  Jeff E Mandel; Jonathan W Tanner; Gary R Lichtenstein; David C Metz; David A Katzka; Gregory G Ginsberg; Michael L Kochman
Journal:  Anesth Analg       Date:  2008-02       Impact factor: 5.108

5.  Oliceridine (TRV130), a Novel G Protein-Biased Ligand at the μ-Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic Model.

Authors:  Michael J Fossler; Brian M Sadler; Colm Farrell; David A Burt; Maria Pitsiu; Franck Skobieranda; David G Soergel
Journal:  J Clin Pharmacol       Date:  2018-02-07       Impact factor: 3.126

6.  Comparison of etomidate-remifentanil and propofol-remifentanil sedation in patients scheduled for colonoscopy.

Authors:  Salime Toklu; Leyla Iyilikci; Can Gonen; Lugen Ciftci; Ferim Gunenc; Elvan Sahin; Erol Gokel
Journal:  Eur J Anaesthesiol       Date:  2009-05       Impact factor: 4.330

7.  Safety and efficacy of combined use of propofol and etomidate for sedation during gastroscopy: Systematic review and meta-analysis.

Authors:  Lingyuan Chen; Xueyan Liang; Xinmei Tan; Haibin Wen; Junsong Jiang; Yan Li
Journal:  Medicine (Baltimore)       Date:  2019-05       Impact factor: 1.817

8.  Procedural Sedation for Pediatric Upper Gastrointestinal Endoscopy in Korea.

Authors:  Yoo Min Lee; Ben Kang; Yu Bin Kim; Hyun Jin Kim; Kyung Jae Lee; Yoon Lee; So Yoon Choi; Eun Hye Lee; Dae Yong Yi; Hyo Jeong Jang; You Jin Choi; Suk Jin Hong; Ju Young Kim; Yunkoo Kang; Soon Chul Kim
Journal:  J Korean Med Sci       Date:  2021-05-24       Impact factor: 2.153

9.  Comparison of clinical efficacy and safety between dexmedetomidine and propofol among patients undergoing gastrointestinal endoscopy: a meta-analysis.

Authors:  Weihua Liu; Wenli Yu; Hongli Yu; Mingwei Sheng
Journal:  J Int Med Res       Date:  2021-07       Impact factor: 1.671

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