Literature DB >> 360231

Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness.

M O Jaskari, U G Ahfors, L Ginman, K Lydekcne, P Tienari.   

Abstract

The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, however, that mianserine had clearly less anticholinergic side-effects than amitriptyline.

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Year:  1977        PMID: 360231     DOI: 10.1055/s-0028-1094526

Source DB:  PubMed          Journal:  Pharmakopsychiatr Neuropsychopharmakol        ISSN: 0031-7098


  8 in total

1.  Phenprocoumon requirement, whole blood coagulation time, bleeding time and plasma gamma-GT in patients receiving mianserin.

Authors:  H Kopera; H Schenk; S Stulemeijer
Journal:  Eur J Clin Pharmacol       Date:  1978-07-30       Impact factor: 2.953

2.  Prejudices in pharmacology and pharmacotherapy. The so-called anticholinergic effect of antidepressants.

Authors:  H J Bein
Journal:  Agents Actions       Date:  1977-09

3.  Mianserin: a decade of scientific development.

Authors:  M Peet; H Behagel
Journal:  Br J Clin Pharmacol       Date:  1978       Impact factor: 4.335

Review 4.  Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-10       Impact factor: 9.546

5.  Mianserin in the treatment of depressive illness and anxiety states in general practice.

Authors:  J E Murphy
Journal:  Br J Clin Pharmacol       Date:  1978       Impact factor: 4.335

6.  Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.

Authors:  G F Perry; B Fitzsimmons; L Shapiro; P Irwin
Journal:  Br J Clin Pharmacol       Date:  1978       Impact factor: 4.335

7.  Behavioural changes during withdrawal from desmethylimipramine (DMI). II. Increased resistance to extinction.

Authors:  P Willner; T Montgomery; D Bird
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

8.  Mianserin in the treatment of depressive illness: A comparison with amitriptyline.

Authors:  R J Daly; P J Browne; E Morgan
Journal:  Ir J Med Sci       Date:  1979-12       Impact factor: 1.568

  8 in total

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