Literature DB >> 36017480

Prevention and Treatment of Monkeypox: A Step-by-Step Guide for Healthcare Professionals and General Population.

Lokesh Goyal1, Kunal Ajmera2, Ramesh Pandit3,4, Trupti Pandit5.   

Abstract

The World Health Organization (WHO) recently declared the monkeypox virus a Public Health Emergency of International Concern (PHEIC). As the cases of the COVID-19 pandemic start to get under control, we have seen the monkeypox virus, found predominantly in Africa, spread in non-endemic countries worldwide. In the 1970s, after the smallpox virus eradication and the vaccine's discontinuation, the monkeypox virus infection started to gain attention. The first United States outbreak happened in 2003; since then, more sporadic cases of monkeypox have gained media attention. With cases spreading worldwide, without epidemiological links with outbreaks among men who have sex with men (MSM), it warrants urgent public health control measures to contain the spread of the monkeypox virus and investigate the underlying pathophysiology, including genetic modification of the virus. This review highlights the epidemiology, transmission, pathogenesis, clinical manifestation, diagnosis, prevention, and management of the current human monkeypox virus infection.
Copyright © 2022, Goyal et al.

Entities:  

Keywords:  lgbtq+; monkeypox prevention; monkeypox rash; monkeypox transmission; monkeypox treatment; monkeypox virus; msm; prevention; public policy

Year:  2022        PMID： 36017480      PMCID： PMC9393027          DOI： 10.7759/cureus.28230

Source DB:  PubMed          Journal:  Cureus        ISSN： 2168-8184


  27 in total

1.  Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein.

Authors:  E L Cooney; A C Collier; P D Greenberg; R W Coombs; J Zarling; D E Arditti; M C Hoffman; S L Hu; L Corey
Journal:  Lancet       Date:  1991-03-09       Impact factor: 79.321

Review 2.  Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.

Authors:  Amanda D Rice; Mathew M Adams; Greg Wallace; Andrew M Burrage; Scott F Lindsey; Andrew J Smith; Daniele Swetnam; Brandi R Manning; Stacey A Gray; Bernhard Lampert; Scott Foster; Randall Lanier; Alice Robertson; George Painter; Richard W Moyer
Journal:  Viruses       Date:  2011-01       Impact factor: 5.048

3.  Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022.

Authors:  John P Thornhill; Sapha Barkati; Sharon Walmsley; Juergen Rockstroh; Andrea Antinori; Luke B Harrison; Romain Palich; Achyuta Nori; Iain Reeves; Maximillian S Habibi; Vanessa Apea; Christoph Boesecke; Linos Vandekerckhove; Michal Yakubovsky; Elena Sendagorta; Jose L Blanco; Eric Florence; Davide Moschese; Fernando M Maltez; Abraham Goorhuis; Valerie Pourcher; Pascal Migaud; Sebastian Noe; Claire Pintado; Fabrizio Maggi; Ann-Brit E Hansen; Christian Hoffmann; Jezer I Lezama; Cristina Mussini; AnnaMaria Cattelan; Keletso Makofane; Darrell Tan; Silvia Nozza; Johannes Nemeth; Marina B Klein; Chloe M Orkin
Journal:  N Engl J Med       Date:  2022-07-21       Impact factor: 176.079

4.  Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022.

Authors:  Agam K Rao; Brett W Petersen; Florence Whitehill; Jafar H Razeq; Stuart N Isaacs; Michael J Merchlinsky; Doug Campos-Outcalt; Rebecca L Morgan; Inger Damon; Pablo J Sánchez; Beth P Bell
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2022-06-03       Impact factor: 35.301

5.  Monkeypox Outbreak - Nine States, May 2022.

Authors:  Faisal S Minhaj; Yasmin P Ogale; Florence Whitehill; Jordan Schultz; Mary Foote; Whitni Davidson; Christine M Hughes; Kimberly Wilkins; Laura Bachmann; Ryan Chatelain; Marisa A P Donnelly; Rafael Mendoza; Barbara L Downes; Mellisa Roskosky; Meghan Barnes; Glen R Gallagher; Nesli Basgoz; Victoria Ruiz; Nang Thu Thu Kyaw; Amanda Feldpausch; Amy Valderrama; Francisco Alvarado-Ramy; Chad H Dowell; Catherine C Chow; Yu Li; Laura Quilter; John Brooks; Demetre C Daskalakis; R Paul McClung; Brett W Petersen; Inger Damon; Christina Hutson; Jennifer McQuiston; Agam K Rao; Ermias Belay; Andrea M McCollum
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2022-06-10       Impact factor: 35.301

6.  Assessing the effectiveness of a community intervention for monkeypox prevention in the Congo basin.

Authors:  Amira A Roess; Benjamin P Monroe; Eric A Kinzoni; Seamus Gallagher; Saturnin R Ibata; Nkenda Badinga; Trolienne M Molouania; Fredy S Mabola; Jean V Mombouli; Darin S Carroll; Adam MacNeil; Noelle A Benzekri; Cynthia Moses; Inger K Damon; Mary G Reynolds
Journal:  PLoS Negl Trop Dis       Date:  2011-10-18

7.  The changing epidemiology of human monkeypox-A potential threat? A systematic review.

Authors:  Eveline M Bunge; Bernard Hoet; Liddy Chen; Florian Lienert; Heinz Weidenthaler; Lorraine R Baer; Robert Steffen
Journal:  PLoS Negl Trop Dis       Date:  2022-02-11

8.  Monkeypox - An emerging pandemic.

Authors:  Kunal M Ajmera; Lokesh Goyal; Trupti Pandit; Ramesh Pandit
Journal:  IDCases       Date:  2022-07-26

Review 9.  Progress in the discovery of compounds inhibiting orthopoxviruses in animal models.

Authors:  Donald F Smee
Journal:  Antivir Chem Chemother       Date:  2008

10.  Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.

Authors:  John Huggins; Arthur Goff; Lisa Hensley; Eric Mucker; Josh Shamblin; Carly Wlazlowski; Wendy Johnson; Jennifer Chapman; Tom Larsen; Nancy Twenhafel; Kevin Karem; Inger K Damon; Chelsea M Byrd; Tove' C Bolken; Robert Jordan; Dennis Hruby
Journal:  Antimicrob Agents Chemother       Date:  2009-04-06       Impact factor: 5.938
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