Literature DB >> 36016967

Man with chest pain.

Saba Choudhry1, Lena Carleton2, Wesley Eilbert2.   

Abstract

Entities:  

Year:  2022        PMID: 36016967      PMCID: PMC9396972          DOI: 10.1002/emp2.12787

Source DB:  PubMed          Journal:  J Am Coll Emerg Physicians Open        ISSN: 2688-1152


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CASE PRESENTATION

A 61‐year‐old man with a history of hypertension and hyperlipidemia presented to the emergency department complaining of a constant left‐sided chest pain present for 1 hour. On examination, his vital signs were normal other than a blood pressure of 180/100 mmHg. He was diaphoretic with an unremarkable cardiopulmonary examination. An echocardiogram (ECG) was performed (Figure 1).
FIGURE 1

de Winter pattern characterized by upsloping ST‐segment depression at the J point in leads V1 to V6 with associated tall and symmetrical T waves. Abbreviation: aVR, augmented vector right lead

de Winter pattern characterized by upsloping ST‐segment depression at the J point in leads V1 to V6 with associated tall and symmetrical T waves. Abbreviation: aVR, augmented vector right lead

DIAGNOSIS

de Winter pattern

First described in 2008, the de Winter pattern on ECG is present in 1.6%–3.4% of anterior wall myocardial infarctions (AWMI). , , , It is characterized by upsloping ST‐segment depression at the J point in the leads V1 to V6 with associated tall, symmetrical T waves. The majority of patients also have ST‐segment elevation in the augmented vector right lead and poor R‐wave progression across the precordial leads, though these 2 features are not essential to make the diagnosis. The de Winter pattern is seen early in the course of AWMI, typically within the first 90 minutes of symptom onset. , It has a positive predictive value of over 95% for AWMI. It is considered by many to be a ST‐segment elevation myocardial infarction equivalent and an indication for emergent reperfusion therapy. , , The vast majority of patients with a de Winter pattern seen on ECG will have occlusion of the proximal left anterior descending coronary artery or one of its main branches , , (Figure 2). Patients with the de Winter pattern as an electrocardiographic manifestation of AWMI are more likely to be male, younger, and with hyperlipidemia.
FIGURE 2

The patient's cardiac catheterization revealing a 100% occlusion of the proximal left anterior descending artery (arrow)

The patient's cardiac catheterization revealing a 100% occlusion of the proximal left anterior descending artery (arrow)
  9 in total

Review 1.  Appropriate cardiac cath lab activation: optimizing electrocardiogram interpretation and clinical decision-making for acute ST-elevation myocardial infarction.

Authors:  Ivan C Rokos; William J French; Amal Mattu; Graham Nichol; Michael E Farkouh; James Reiffel; Gregg W Stone
Journal:  Am Heart J       Date:  2010-12       Impact factor: 4.749

2.  A new ECG sign of proximal LAD occlusion.

Authors:  Robbert J de Winter; Niels J W Verouden; Hein J J Wellens; Arthur A M Wilde
Journal:  N Engl J Med       Date:  2008-11-06       Impact factor: 91.245

3.  A new electrocardiographic criteria for emergent reperfusion therapy.

Authors:  Jacob R Hennings; Francis M Fesmire
Journal:  Am J Emerg Med       Date:  2011-06-23       Impact factor: 2.469

4.  Prevalence of junctional ST-depression with tall symmetrical T-waves in a pre-hospital field triage system for STEMI patients.

Authors:  Ruben W de Winter; Rob Adams; Giovanni Amoroso; Yolande Appelman; Lucia Ten Brinke; Bart Huybrechts; Pieternel van Exter; Robbert J de Winter
Journal:  J Electrocardiol       Date:  2018-10-18       Impact factor: 1.438

5.  Persistent precordial "hyperacute" T-waves signify proximal left anterior descending artery occlusion.

Authors:  N J Verouden; K T Koch; R J Peters; J P Henriques; J Baan; R J van der Schaaf; M M Vis; J G Tijssen; J J Piek; H J Wellens; A A Wilde; R J de Winter
Journal:  Heart       Date:  2009-07-19       Impact factor: 5.994

6.  The de winter electrocardiogram pattern is a transient electrocardiographic phenomenon that presents at the early stage of ST-segment elevation myocardial infarction.

Authors:  Jing Xu; Aihua Wang; Li Liu; Zijun Chen
Journal:  Clin Cardiol       Date:  2018-09-22       Impact factor: 2.882

Review 7.  The De Winter ECG pattern: morphology and accuracy for diagnosing acute coronary occlusion: systematic review.

Authors:  Niall P Morris; Richard Body
Journal:  Eur J Emerg Med       Date:  2017-08       Impact factor: 2.799

8.  Man with chest discomfort.

Authors:  Molly Hartrich; Wesley Eilbert; Amy Eisenberg
Journal:  J Am Coll Emerg Physicians Open       Date:  2022-04-18

9.  A Novel Electrocardiographic Sign of an ST-Segment Elevation Myocardial Infarction-Equivalent: De Winter Syndrome.

Authors:  Mustafa Ugur Goktas; Ozgur Sogut; Mehmet Yigit; Onur Kaplan
Journal:  Cardiol Res       Date:  2017-08-23
  9 in total

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