Literature DB >> 3600646

Developmental regulation of DNase I-hypersensitive sites in Dictyostelium discoideum.

K Ayres, W Neuman, W G Rowekamp, S Chung.   

Abstract

We have studied two regions of Dictyostelium discoideum chromatin and identified several DNase I-hypersensitive sites in these regions. One of these sites is located about 300 to 500 bases upstream of the transcriptional start site of a gene that is expressed at all stages of development. This site is present in both vegetative cells and postaggregation cells. Another hypersensitive site is associated with a gene that is expressed only after the multicellular stage. This site is located about 400 bases upstream of the start site, and it is present only in postaggregation cells. Thus, much like higher eucaryotes, D. discoideum contains DNase I-hypersensitive sites that may be involved in the regulation of the genes with which they are associated.

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Year:  1987        PMID： 3600646      PMCID： PMC365285          DOI： 10.1128/mcb.7.5.1823-1829.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  29 in total

1.  Heterogeneity and 5'-terminal structures of the late RNAs of simian virus 40.

Authors:  P K Ghosh; V B Reddy; J Swinscoe; P Lebowitz; S M Weissman
Journal:  J Mol Biol       Date:  1978-12-25       Impact factor: 5.469

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters.

Authors:  D C Lee; R G Roeder
Journal:  Mol Cell Biol       Date:  1981-07       Impact factor: 4.272

4.  The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence.

Authors:  C Wu; P M Bingham; K J Livak; R Holmgren; S C Elgin
Journal:  Cell       Date:  1979-04       Impact factor: 41.582

5.  Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonuclease.

Authors:  D R Hewish; L A Burgoyne
Journal:  Biochem Biophys Res Commun       Date:  1973-05-15       Impact factor: 3.575

6.  Sensitivity of Dictyostelium discoideum to nucleic acid analogues.

Authors:  W F Loomis
Journal:  Exp Cell Res       Date:  1971-02       Impact factor: 3.905

7.  A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cells.

Authors:  K Müller; G Gerisch
Journal:  Nature       Date:  1978-08-03       Impact factor: 49.962

8.  Developmental changes in messenger RNAs and protein synthesis in Dictyostelium discoideum.

Authors:  T H Alton; H F Lodish
Journal:  Dev Biol       Date:  1977-10-01       Impact factor: 3.582

9.  Hypersensitive sites in the 5' and 3' flanking regions of the cysteine proteinase I gene of Dictyostelium discoideum.

Authors:  J Pavlovic; E Banz; R W Parish
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

10.  Regulated expression of ras gene constructs in Dictyostelium transformants.

Authors:  C D Reymond; W Nellen; R A Firtel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205
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  6 in total

1.  Association of a change in chromatin structure with a tissue-specific switch in transcription start sites in the alpha 2(I) collagen gene.

Authors:  K M Beck; A H Seekamp; G R Askew; Z Mei; C M Farrell; S Wang; L N Lukens
Journal:  Nucleic Acids Res       Date:  1991-09-25       Impact factor: 16.971

2.  Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP.

Authors:  F Vauti; P Morandini; J Blusch; A Sachse; W Nellen
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

3.  Nuclear pre-mRNA introns: analysis and comparison of intron sequences from Tetrahymena thermophila and other eukaryotes.

Authors:  C Csank; F M Taylor; D W Martindale
Journal:  Nucleic Acids Res       Date:  1990-09-11       Impact factor: 16.971

4.  The molecular basis for alternative splicing of the CABP1 transcripts in Dictyostelium discoideum.

Authors:  C E Grant; G Bain; A Tsang
Journal:  Nucleic Acids Res       Date:  1990-09-25       Impact factor: 16.971

5.  Multiple copies of a G-rich element upstream of a cAMP-inducible Dictyostelium gene are necessary but not sufficient for efficient gene expression.

Authors:  C J Pears; J G Williams
Journal:  Nucleic Acids Res       Date:  1988-09-12       Impact factor: 16.971

6.  Identification of a signal transduction response sequence element necessary for induction of a Dictyostelium discoideum gene by extracellular cyclic AMP.

Authors:  J Pavlovic; B Haribabu; R P Dottin
Journal:  Mol Cell Biol       Date:  1989-11       Impact factor: 4.272
  6 in total

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