Carl E Orringer1, Jelani K Grant2, Lale Tokgozoglu3. 1. Department of Medicine, Cardiovascular Division, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1111, Miami, FL, 33136, USA. ceo20@miami.edu. 2. Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 3. Department of Cardiology, Hacettepe University, Ankara, Turkey.
Abstract
PURPOSE OF REVIEW: To provide a systematic approach to management of the patient with statin-attributed muscle symptoms. RECENT FINDINGS: We examined the prevalence of statin intolerance, the role of the nocebo effect, key findings in the patient's history and laboratory studies, the potential value of coronary calcium scoring, and the importance of shared decision-making in considering statin re-initiation. Most patients with statin-attributed muscle symptoms can be successfully treated with statins or a combination of statins and non-statins to achieve successful ASCVD risk reduction.
PURPOSE OF REVIEW: To provide a systematic approach to management of the patient with statin-attributed muscle symptoms. RECENT FINDINGS: We examined the prevalence of statin intolerance, the role of the nocebo effect, key findings in the patient's history and laboratory studies, the potential value of coronary calcium scoring, and the importance of shared decision-making in considering statin re-initiation. Most patients with statin-attributed muscle symptoms can be successfully treated with statins or a combination of statins and non-statins to achieve successful ASCVD risk reduction.
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