Literature DB >> 35999903

Symptoms Originally Attributed to Thyroid Dysfunction Were Instead Caused by Suboptimal Gastrointestinal Health: A Case Series and Literature Review.

Michael Ruscio1, Gavin Guard1, Joe Mather1.   

Abstract

The integrative and functional medicine field has drifted towards a thyroid-centric approach of care (fine-tune thyroid medication, support thyroid hormone conversion, and improve thyroid levels). However, many patients still do not improve symptomatically. Here, we show how a gut-focused clinical care model can improve thyroid function, reduce thyroid medication dose, and improve symptoms originally thought to be from thyroid dysfunction. We present a literature review on the gutthyroid axis and then document clinical application of this evidence through six case reports of how patients improved thyroid function and thyroid-related symptoms by improving their gastrointestinal health. Clinicians will likely experience better patient outcomes by integrating the contents of this paper into their practice.
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Entities:  

Year:  2022        PMID: 35999903      PMCID: PMC9380837     

Source DB:  PubMed          Journal:  Integr Med (Encinitas)        ISSN: 1546-993X


  43 in total

1.  Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis.

Authors:  Marco Centanni; Lucilla Gargano; Gianluca Canettieri; Nicola Viceconti; Antonella Franchi; Gianfranco Delle Fave; Bruno Annibale
Journal:  N Engl J Med       Date:  2006-04-27       Impact factor: 91.245

2.  Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults.

Authors:  Chengcheng Zhang; Jinchi Jiang; Fengwei Tian; Jianxin Zhao; Hao Zhang; Qixiao Zhai; Wei Chen
Journal:  Clin Nutr       Date:  2020-01-14       Impact factor: 7.324

3.  The role of Helicobacter pylori in patients with hypothyroidism in whom could not be achieved normal thyrotropin levels despite treatment with high doses of thyroxine.

Authors:  Mehmet Sait Bugdaci; Sayid Shafi Zuhur; Mehmet Sokmen; Buket Toksoy; Banu Bayraktar; Banu Albayrak; Yüksel Altuntas
Journal:  Helicobacter       Date:  2011-04       Impact factor: 5.753

4.  Effects of Probiotic Use on Quality of Life and Physical Activity in Constipated Female University Students: A Randomized, Double-Blind Placebo-Controlled Study.

Authors:  Michelle Jalousie Kommers; Rosilene Andrade Silva Rodrigues; Fábio Miyajima; Arturo Alejandro Zavala Zavala; Viviane Regina Leite Moreno Ultramari; Waléria Christiane Rezende Fett; Sikiru Olaitan Balogun; Ruberlei Godinho de Oliveira; Carlos Alexandre Fett
Journal:  J Altern Complement Med       Date:  2019-10-29       Impact factor: 2.579

5.  Transient high thyroid stimulating hormone and hypothyroidism incidence during follow up of subclinical hypothyroidism.

Authors:  Munir Abu-Helalah; Hussam Ahmad Alshraideh; Sameeh Abdulkareem Al-Sarayreh; AbdelFattah Al-Hader
Journal:  Endocr Regul       Date:  2021-12-07

Review 6.  Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Ruixue Huang; Ke Wang; Jianan Hu
Journal:  Nutrients       Date:  2016-08-06       Impact factor: 5.717

7.  Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism.

Authors:  Simon P Mooijaart; Robert S Du Puy; David J Stott; Patricia M Kearney; Nicolas Rodondi; Rudi G J Westendorp; Wendy P J den Elzen; Iris Postmus; Rosalinde K E Poortvliet; Diana van Heemst; Barbara C van Munster; Robin P Peeters; Ian Ford; Sharon Kean; Claudia-Martina Messow; Manuel R Blum; Tinh-Hai Collet; Torquil Watt; Olaf M Dekkers; J Wouter Jukema; Johannes W A Smit; Peter Langhorne; Jacobijn Gussekloo
Journal:  JAMA       Date:  2019-11-26       Impact factor: 56.272

Review 8.  The epidemiology of irritable bowel syndrome.

Authors:  Caroline Canavan; Joe West; Timothy Card
Journal:  Clin Epidemiol       Date:  2014-02-04       Impact factor: 4.790

9.  Short-course Rifaximin therapy efficacy and lactulose hydrogen breath test in Chinese patients with diarrhea-predominant irritable bowel syndrome.

Authors:  Xiaojun Zhuang; Zhenyi Tian; Mei Luo; Lishou Xiong
Journal:  BMC Gastroenterol       Date:  2020-06-12       Impact factor: 3.067

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  1 in total

Review 1.  The Relationship between Gastrointestinal Health, Micronutrient Concentrations, and Autoimmunity: A Focus on the Thyroid.

Authors:  Michael Ruscio; Gavin Guard; Gabriela Piedrahita; Christopher R D'Adamo
Journal:  Nutrients       Date:  2022-08-30       Impact factor: 6.706

  1 in total

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