| Literature DB >> 35991696 |
Tung Phan1, Masaaki Kobayashi2, Koo Nagasawa3, Riona Hatazawa4, Ngan Thi Kim Pham5, Hideaki Miyashita2, Satoshi Komoto4, Takeshi Tajima2, Tuneyoshi Baba2, Shoko Okitsu5, Pattara Khamrin6, Niwat Maneekarn6, Hirokazu Kimura7, Takeshi Kobayashi8, Satoshi Hayakawa5, Hiroshi Ushijima5.
Abstract
Unusual DS-1-like intergenogroup reassortant rotaviruses with a bovine-like G8 genotype (DS-1-like G8P [8] rotaviruses) have emerged and rapidly spread in several countries. In this study, the nucleotide sequences of seven human rotavirus G8P [8] strains in 2017 and 2019 in Japan were determined using viral metagenomics. Its genomic constellation (VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5 genes) was defined as G8-P [8]-I2-R2-C2-M2-A2-N2-T2-E2-H2. Our genetic analysis revealed that the Japanese G8P [8] rotavirus strains in 2017 and 2019 were classified into the same lineages G8-5 and P [8]-3, but they were phylogenetically located on separate branches and belonged to distinct clusters. Our study is the first attempt to investigate the evolution of emerging rotavirus G8P [8] in Japan.Entities:
Keywords: Emergence; G8P [8]; Genomic analysis; Rotavirus; Whole genome sequencing
Year: 2022 PMID： 35991696 PMCID： PMC9381655 DOI： 10.1007/s13337-022-00765-z
Source DB: PubMed Journal: Virusdisease ISSN： 2347-3584