Literature DB >> 35990789

Barriers to hepatitis C diagnosis and treatment in the DAA era: Preliminary results of a community-based survey of primary care practitioners.

Sanjeev Sirpal1, Natasha Chandok2.   

Abstract

Notwithstanding the groundbreaking achievement of hepatitis C curative treatment with direct-acting antiviral therapies, Canada faces an uphill battle in reaching the 2030 goal of viral elimination set forth by the World Health Organization, a goal made more difficult by the COVID-19 pandemic. There is limited understanding of the diagnostic and treatment barriers, and challenges in linkage to care in Canada, especially as it pertains to primary care providers in a community context. Therefore, in this article, the authors conducted a survey study to evaluate the following factors: primary care providers' knowledge of specialist treatment options and the importance of screening and treatment; and patient factors, including transportation, linguistic barriers, and other socio-economic status indicators that impact the screening and management of hepatitis C. The results suggest that public health campaigns that protocolize and/or incentivize screening and referrals may provide solutions to addressing such barriers.
Copyright © 2022 Canadian Association for the Study of the Liver.

Entities:  

Keywords:  DAA; barriers; diagnosis; hepatitis C; treatment

Year:  2022        PMID: 35990789      PMCID: PMC9231428          DOI: 10.3138/canlivj-2021-0032

Source DB:  PubMed          Journal:  Can Liver J        ISSN: 2561-4444


  12 in total

Review 1.  Novel Models of Hepatitis C Virus Care Delivery: Telemedicine, Project ECHO, and Integrative Care.

Authors:  Sanjeev Arora; Karla Thornton
Journal:  Clin Liver Dis (Hoboken)       Date:  2020-07-21

2.  The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver.

Authors:  Hemant Shah; Marc Bilodeau; Kelly W Burak; Curtis Cooper; Marina Klein; Alnoor Ramji; Dan Smyth; Jordan J Feld
Journal:  CMAJ       Date:  2018-06-04       Impact factor: 8.262

Review 3.  Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure?

Authors:  Tarik Asselah; Patrick Marcellin; Raymond F Schinazi
Journal:  Liver Int       Date:  2018-02       Impact factor: 5.828

Review 4.  We know DAAs work, so now what? Simplifying models of care to enhance the hepatitis C cascade.

Authors:  J V Lazarus; J M Pericàs; C Picchio; J Cernosa; M Hoekstra; N Luhmann; M Maticic; P Read; E M Robinson; J F Dillon
Journal:  J Intern Med       Date:  2019-10-04       Impact factor: 8.989

5.  Expansion of Treatment for Hepatitis C Virus Infection by Task Shifting to Community-Based Nonspecialist Providers: A Nonrandomized Clinical Trial.

Authors:  Sarah Kattakuzhy; Chloe Gross; Benjamin Emmanuel; Gebeyehu Teferi; Veronica Jenkins; Rachel Silk; Elizabeth Akoth; Aurielle Thomas; Charisse Ahmed; Michelle Espinosa; Angie Price; Elana Rosenthal; Lydia Tang; Eleanor Wilson; Soren Bentzen; Henry Masur; Shyam Kottilil
Journal:  Ann Intern Med       Date:  2017-08-08       Impact factor: 25.391

6.  Hepatitis C Virus Eradication with New Interferon-Free Treatment Improves Metabolic Profile in Hepatitis C Virus-Related Liver Transplant Recipients.

Authors:  Junaid Beig; David Orr; Barry Harrison; Edward Gane
Journal:  Liver Transpl       Date:  2018-08       Impact factor: 5.799

7.  Aiming for elimination: Outcomes of a consultation pathway supporting regional general practitioners to prescribe direct-acting antiviral therapy for hepatitis C.

Authors:  A J Wade; A McCormack; C Roder; K McDonald; M Davies; N Scott; M Wardrop; E Athan; M E Hellard
Journal:  J Viral Hepat       Date:  2018-05-08       Impact factor: 3.728

8.  Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States.

Authors:  Jagpreet Chhatwal; Fasiha Kanwal; Mark S Roberts; Michael A Dunn
Journal:  Ann Intern Med       Date:  2015-03-17       Impact factor: 25.391

9.  Cost-effectiveness of Hepatitis C Virus Treatment Models for People Who Inject Drugs in Opioid Agonist Treatment Programs.

Authors:  Sarah Gutkind; Bruce R Schackman; Jake R Morgan; Jared A Leff; Linda Agyemang; Sean M Murphy; Matthew J Akiyama; Brianna L Norton; Alain H Litwin; Benjamin P Linas
Journal:  Clin Infect Dis       Date:  2020-03-17       Impact factor: 20.999

10.  Telemedicine, COVID-19 and liver diseases: Revamping remote care initiatives in hepatology.

Authors:  Marco Arrese
Journal:  Ann Hepatol       Date:  2020-05-23       Impact factor: 2.400

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