Literature DB >> 35990221

Cannabis and the liver: Things you wanted to know but were afraid to ask.

Julie Zhu1, Kevork M Peltekian1.   

Abstract

Many Canadians use cannabis for medicinal and recreational purposes. We describe the current understandings of how cannabis is metabolized in the liver and its potential interactions with other common drugs. We also summarize how cannabis may exert various effects in chronic liver diseases (CLDs), especially in chronic hepatitis C virus (HCV) and fatty liver disease.
Copyright © 2019 Canadian Association for the Study of the Liver.

Entities:  

Keywords:  cannabidiol; cannabis; chronic liver disease; pharmacokinetics; tetrahydrocannabinol

Year:  2019        PMID: 35990221      PMCID: PMC9202751          DOI: 10.3138/canlivj.2018-0023

Source DB:  PubMed          Journal:  Can Liver J        ISSN: 2561-4444


  38 in total

1.  Potential role of CB2 receptors in Cannabis smokers with chronic hepatitis C.

Authors:  Robert F Schwabe; Soeren V Siegmund
Journal:  Hepatology       Date:  2005-10       Impact factor: 17.425

2.  Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death.

Authors:  Partha Mukhopadhyay; Mohanraj Rajesh; Béla Horváth; Sándor Bátkai; Ogyi Park; Galin Tanchian; Rachel Y Gao; Vivek Patel; David A Wink; Lucas Liaudet; György Haskó; Raphael Mechoulam; Pál Pacher
Journal:  Free Radic Biol Med       Date:  2011-03-11       Impact factor: 7.376

3.  Recreational marijuana use is not associated with worse outcomes after renal transplantation.

Authors:  Garrett Greenan; Sarwat B Ahmad; Megan G Anders; Alexia Leeser; Jonathan S Bromberg; Silke V Niederhaus
Journal:  Clin Transplant       Date:  2016-09-05       Impact factor: 2.863

4.  Cannabinoid receptor type I modulates alcohol-induced liver fibrosis.

Authors:  Eleonora Patsenker; Matthias Stoll; Gunda Millonig; Abbas Agaimy; Till Wissniowski; Vreni Schneider; Sebastian Mueller; Rudolf Brenneisen; Helmut K Seitz; Matthias Ocker; Felix Stickel
Journal:  Mol Med       Date:  2011-08-19       Impact factor: 6.354

5.  CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.

Authors:  Fatima Teixeira-Clerc; Boris Julien; Pascale Grenard; Jeanne Tran Van Nhieu; Vanessa Deveaux; Liying Li; Valérie Serriere-Lanneau; Catherine Ledent; Ariane Mallat; Sophie Lotersztajn
Journal:  Nat Med       Date:  2006-05-21       Impact factor: 53.440

Review 6.  Pharmacokinetics and pharmacodynamics of cannabinoids.

Authors:  Franjo Grotenhermen
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

Review 7.  Marijuana Use and Organ Transplantation: a Review and Implications for Clinical Practice.

Authors:  Harinder Singh Rai; Gerald Scott Winder
Journal:  Curr Psychiatry Rep       Date:  2017-10-27       Impact factor: 5.285

8.  Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C.

Authors:  Christophe Hézode; Elie Serge Zafrani; Françoise Roudot-Thoraval; Charlotte Costentin; Ali Hessami; Magali Bouvier-Alias; Fatiha Medkour; Jean-Michel Pawlostky; Sophie Lotersztajn; Ariane Mallat
Journal:  Gastroenterology       Date:  2007-11-28       Impact factor: 22.682

Review 9.  Cannabis in liver disorders: a friend or a foe?

Authors:  Hemant Goyal; M Rubayat Rahman; Abhilash Perisetti; Nihar Shah; Rajiv Chhabra
Journal:  Eur J Gastroenterol Hepatol       Date:  2018-11       Impact factor: 2.566

Review 10.  Acute cannabis consumption and motor vehicle collision risk: systematic review of observational studies and meta-analysis.

Authors:  Mark Asbridge; Jill A Hayden; Jennifer L Cartwright
Journal:  BMJ       Date:  2012-02-09
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  1 in total

Review 1.  Cannabinoids and Chronic Liver Diseases.

Authors:  Ralph-Sydney Mboumba Bouassa; Giada Sebastiani; Vincenzo Di Marzo; Mohammad-Ali Jenabian; Cecilia T Costiniuk
Journal:  Int J Mol Sci       Date:  2022-08-20       Impact factor: 6.208

  1 in total

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