Literature DB >> 3598881

Toxicity of chloroform and bromodichloromethane when administered over a lifetime in rats.

C F Tumasonis, D N McMartin, B Bush.   

Abstract

Chloroform (CHCl3) and bromodichloromethane (CHBrCl2) are the two most common haloorganic contaminants of chlorinated drinking water. A significantly increased incidence of hepatic neoplastic nodules was found in female rats when either of these compounds was administered in drinking water to Wistar rats throughout their life-span. Hepatic adenofibrosis was also produced by chronic ingestion of these two halomethanes.

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Year:  1987        PMID: 3598881

Source DB:  PubMed          Journal:  J Environ Pathol Toxicol Oncol        ISSN: 0731-8898            Impact factor:   3.567


  2 in total

Review 1.  Colorectal cancers and chlorinated water.

Authors:  Ahmed Mahmoud El-Tawil
Journal:  World J Gastrointest Oncol       Date:  2016-04-15

2.  Effects of chloroform and bromodichloromethane on DNA synthesis in male F344 rat kidney.

Authors:  M M Lipsky; M Skinner; C O'Connell
Journal:  Environ Health Perspect       Date:  1993-12       Impact factor: 9.031

  2 in total

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