| Literature DB >> 3597523 |
S Martino, V Ratanatharathorn, C Karanes, B A Samal, Y H Sohn, S A Rudnick.
Abstract
We have treated 25 patients, 7 with breast cancer and 18 with non-Hodgkin's lymphoma, with recombinant alpha 2 interferon. In 5 patients we observed cardiac arrhythmias that were unexpected and required treatment. No deaths have occurred that we can attribute to interferon, though 1 patient had to be resuscitated. Age, prior cardiac disease, prior treatment with doxorubicin, and interferon dose appear to be predisposing factors for this toxicity.Entities:
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Year: 1987 PMID： 3597523 DOI： 10.1007/bf00397722
Source DB: PubMed Journal: J Cancer Res Clin Oncol ISSN： 0171-5216 Impact factor: 4.553