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Literature DB >> 359750

The cellular basis of allograft rejection in vivo. I. The cellular requirements for first-set rejection of heart grafts.

Abstract

The nature of the cells required for first-set graft rejection in vivo was examined by using an adoptive transfer system to restore heart-graft rejection in irradiated rats. Highly purified inocula of peripheral T lymphocytes were shown to quantitatively account for the restorative ability of adoptively transferred cells. These T cells were shown to be long-lived small lymphocytes which are not recently derived from the thymus during adult life. They belong to the pool of T cells which constantly recirculate from blood to lymph as shown by their rapid appearance in the lymph of iradiated syngeneic rats after intravenous injection. Neither B lymphocytes nor antibodies in the circulation or in the graft itself are required for first-set graft rejection.

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Year: 1978 PMID： 359750 PMCID： PMC2185031 DOI： 10.1084/jem.148.4.878

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

30 in total

1. Magnitude of memory to the major histocompatibility complex.

Authors: B M Hall; B J Roser; S E Dorsch
Journal: Nature Date: 1977-08-11 Impact factor: 49.962

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Authors: D D MCGREGOR; J L GOWANS
Journal: Lancet Date: 1964-03-21 Impact factor: 79.321

3. THE ROUTE OF RE-CIRCULATION OF LYMPHOCYTES IN THE RAT.

Authors: J L GOWANS; E J KNIGHT
Journal: Proc R Soc Lond B Biol Sci Date: 1964-01-14

4. In vitro correlates of rejection. II. Rat mixed lymphocyte reactivity in vitro and cardiac allograft acute rejection, hyperacute or accelerated rejection, and prolongation by active immunization.

Authors: R D Guttmann
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5. Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.

Authors: A F Williams; G Galfrè; C Milstein
Journal: Cell Date: 1977-11 Impact factor: 41.582

6. Demonstration of theta-AKR differentiation antigen in rat tissue by mouse alloantiserum.

Authors: B Micheel; G Pasternak; J Steuden
Journal: Nat New Biol Date: 1973-02-14

7. Mouse lymphocytes with and without surface immunoglobulin: preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin.

Authors: M G Mage; L L McHugh; T L Rothstein
Journal: J Immunol Methods Date: 1977 Impact factor: 2.303

8. The covalent coupling of proteins to periodate-oxidized sephadex: a new approach to immunoadsorbent preparation.

Authors: M B Wilson; P K Nakane
Journal: J Immunol Methods Date: 1976 Impact factor: 2.303

9. Recirculating, suppressor T cells in transplantation tolerance.

Authors: S Dorsch; R Roser
Journal: J Exp Med Date: 1977-05-01 Impact factor: 14.307

10. Role of the thymus in immune reactions in rats. II. Suppressive effect of thymectomy at birth on reactions of delayed (cellular) hypersensitivity and the circulating small lymphocyte.

Authors: B G ARNASON; B D JANKOVIC; B H WAKSMAN; C WENNERSTEN
Journal: J Exp Med Date: 1962-08-01 Impact factor: 14.307

31 in total

Review 1. The effect of locally synthesised complement on acute renal allograft rejection.

Authors: Steven Sacks; Wuding Zhou
Journal: J Mol Med (Berl) Date: 2003-06-25 Impact factor: 4.599

2. Prolongation of rat corneal graft survival by treatment with anti-CD4 monoclonal antibody.

Authors: W Ayliffe; Y Alam; E B Bell; D McLeod; I V Hutchinson
Journal: Br J Ophthalmol Date: 1992-10 Impact factor: 4.638

Review 3. T Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T Cells.

Authors: Bruce M Hall
Journal: Clin J Am Soc Nephrol Date: 2015-04-15 Impact factor: 8.237

Review 4. The innate immune system in transplantation.

Authors: Martin H Oberbarnscheidt; Daniel Zecher; Fadi G Lakkis
Journal: Semin Immunol Date: 2011-07-01 Impact factor: 11.130

5. Four-Dimensional Imaging of T Cells in Kidney Transplant Rejection.

Authors: Andrew D Hughes; Fadi G Lakkis; Martin H Oberbarnscheidt
Journal: J Am Soc Nephrol Date: 2018-04-13 Impact factor: 10.121

6. A controlled serial ultrastructural tracer study of first-set cardiac allograft rejection in the rat. Evidence that the microvascular endothelium is the primary target of graft destruction.

Authors: R D Forbes; R D Guttmann; M Gomersall; J Hibberd
Journal: Am J Pathol Date: 1983-05 Impact factor: 4.307

7. Allograft rejection in athymic nude rats by transferred T-cell subsets. I. The response of naive CD4+ and CD8+ thoracic duct lymphocytes to complete allogeneic incompatibilities.

Authors: E H Whitby; S M Sparshott; E B Bell
Journal: Immunology Date: 1990-01 Impact factor: 7.397

8. Innate immunity alone is not sufficient for chronic rejection but predisposes healed allografts to T cell-mediated pathology.

Authors: Daniel Zecher; Qi Li; Amanda L Williams; John T Walters; Fady K Baddoura; Geetha Chalasani; David M Rothstein; Warren D Shlomchik; Anthony J Demetris; Fadi G Lakkis
Journal: Transpl Immunol Date: 2011-12-24 Impact factor: 1.708

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Authors: I Date; K Kawamura; H Nakashima
Journal: Exp Brain Res Date: 1988 Impact factor: 1.972

10. T-cell activation, proliferation, and memory after cardiac transplantation in vivo.

Authors: N D Jones; A Van Maurik; M Hara; B J Gilot; P J Morris; K J Wood
Journal: Ann Surg Date: 1999-04 Impact factor: 12.969