Literature DB >> 35974425

Respiratory Reviews in Asthma 2022.

Ji Hye Lee1, Jin-Young Kim1, Jae Sung Choi1, Ju Ock Na1.   

Abstract

Asthma is a chronic inflammatory disease of the airways characterized by varying and recurrent symptoms, reversible airway obstruction, and bronchospasm. In this paper, clinical important studies on asthma published between March 2021 and February 2022 were reviewed. A study on the relationship between asthma and chronic rhinosinusitis, bronchiectasis, and hormone replacement therapy was published. A journal on the usefulness of fractional exhaled nitric oxide for the prediction of severe acute exacerbation was also introduced. Studies on the effect of inhaler, one of the most important treatments for asthma, were published. Studies on the control of severe asthma continued. Phase 2 and 3 studies of new biologics were also published. As the coronavirus disease 2019 (COVID-19) pandemic has been prolonged, many studies have explored the prevalence and mortality of COVID-19 infection in asthma patients.

Entities:  

Keywords:  Asthma; Biologics; COVID-19; Fractional Exhaled Nitric Oxide; Inhaler Therapy

Year:  2022        PMID: 35974425      PMCID: PMC9537659          DOI: 10.4046/trd.2022.0097

Source DB:  PubMed          Journal:  Tuberc Respir Dis (Seoul)        ISSN: 1738-3536


  21 in total

1.  Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial.

Authors:  Steven G Kelsen; Ioana O Agache; Weily Soong; Elliot Israel; Geoffrey L Chupp; Dorothy S Cheung; Wiebke Theess; Xiaoying Yang; Tracy L Staton; David F Choy; Alice Fong; Ajit Dash; Michael Dolton; Rajita Pappu; Christopher E Brightling
Journal:  J Allergy Clin Immunol       Date:  2021-04-16       Impact factor: 10.793

2.  Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.

Authors:  Andrew Menzies-Gow; Jonathan Corren; Arnaud Bourdin; Geoffrey Chupp; Elliot Israel; Michael E Wechsler; Christopher E Brightling; Janet M Griffiths; Åsa Hellqvist; Karin Bowen; Primal Kaur; Gun Almqvist; Sandhia Ponnarambil; Gene Colice
Journal:  N Engl J Med       Date:  2021-05-13       Impact factor: 91.245

3.  Long-term safety and efficacy of dupilumab in patients with moderate-to-severe asthma (TRAVERSE): an open-label extension study.

Authors:  Michael E Wechsler; Linda B Ford; Jorge F Maspero; Ian D Pavord; Alberto Papi; Arnaud Bourdin; Henrik Watz; Mario Castro; Natalia M Nenasheva; Yuji Tohda; David Langton; Guido Cardona; Christian Domingo; Hae Sim Park; Kenneth R Chapman; Xuezhou Mao; Yi Zhang; Asif H Khan; Yamo Deniz; Paul J Rowe; Upender Kapoor; Faisal A Khokhar; Leda P Mannent; Marcella Ruddy; Elizabeth Laws; Nikhil Amin; Megan Hardin
Journal:  Lancet Respir Med       Date:  2021-09-28       Impact factor: 30.700

4.  Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment.

Authors:  Natalie M Niessen; Peter G Gibson; Katherine J Baines; Daniel Barker; Ian A Yang; John W Upham; Paul N Reynolds; Sandra Hodge; Alan L James; Christine Jenkins; Matthew J Peters; Guy B Marks; Melissa Baraket; Jodie L Simpson; Michael Fricker
Journal:  Allergy       Date:  2021-03-02       Impact factor: 13.146

5.  The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given 'as needed' in mild asthma: study protocols for two randomised controlled trials.

Authors:  Paul M O'Byrne; J Mark FitzGerald; Nanshan Zhong; Eric Bateman; Peter J Barnes; Christina Keen; Gun Almqvist; Kristine Pemberton; Carin Jorup; Stefan Ivanov; Helen K Reddel
Journal:  Trials       Date:  2017-01-10       Impact factor: 2.279

6.  COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.

Authors:  Michael C Peters; Satria Sajuthi; Peter Deford; Stephanie Christenson; Cydney L Rios; Michael T Montgomery; Prescott G Woodruff; David T Mauger; Serpil C Erzurum; Mats W Johansson; Loren C Denlinger; Nizar N Jarjour; Mario Castro; Annette T Hastie; Wendy Moore; Victor E Ortega; Eugene R Bleecker; Sally E Wenzel; Elliot Israel; Bruce D Levy; Max A Seibold; John V Fahy
Journal:  Am J Respir Crit Care Med       Date:  2020-07-01       Impact factor: 21.405

Review 7.  Anti-alarmins in asthma: targeting the airway epithelium with next-generation biologics.

Authors:  Celeste M Porsbjerg; Asger Sverrild; Clare M Lloyd; Andrew N Menzies-Gow; Elisabeth H Bel
Journal:  Eur Respir J       Date:  2020-11-12       Impact factor: 16.671

8.  Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.

Authors:  Sumita B Khatri; Jonathan M Iaccarino; Amisha Barochia; Israa Soghier; Praveen Akuthota; Anna Brady; Ronina A Covar; Jason S Debley; Zuzana Diamant; Anne M Fitzpatrick; David A Kaminsky; Nicholas J Kenyon; Sandhya Khurana; Brian J Lipworth; Kevin McCarthy; Michael Peters; Loretta G Que; Kristie R Ross; Elena K Schneider-Futschik; Christine A Sorkness; Teal S Hallstrand
Journal:  Am J Respir Crit Care Med       Date:  2021-11-15       Impact factor: 21.405

9.  Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma.

Authors:  William W Busse; Jorge F Maspero; Klaus F Rabe; Alberto Papi; Sally E Wenzel; Linda B Ford; Ian D Pavord; Bingzhi Zhang; Heribert Staudinger; Gianluca Pirozzi; Nikhil Amin; Bolanle Akinlade; Laurent Eckert; Jingdong Chao; Neil M H Graham; Ariel Teper
Journal:  Adv Ther       Date:  2018-05-03       Impact factor: 3.845

10.  Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform.

Authors:  Anna Schultze; Alex J Walker; Brian MacKenna; Caroline E Morton; Krishnan Bhaskaran; Jeremy P Brown; Christopher T Rentsch; Elizabeth Williamson; Henry Drysdale; Richard Croker; Seb Bacon; William Hulme; Chris Bates; Helen J Curtis; Amir Mehrkar; David Evans; Peter Inglesby; Jonathan Cockburn; Helen I McDonald; Laurie Tomlinson; Rohini Mathur; Kevin Wing; Angel Y S Wong; Harriet Forbes; John Parry; Frank Hester; Sam Harper; Stephen J W Evans; Jennifer Quint; Liam Smeeth; Ian J Douglas; Ben Goldacre
Journal:  Lancet Respir Med       Date:  2020-09-24       Impact factor: 30.700

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