| Literature DB >> 35974068 |
Sirui Song1, Xue Liu1, Yong Li2, Yang Yu3,4.
Abstract
Mobility-control policy is a controversial nonpharmacological approach to pandemic control due to its restriction on people's liberty and economic impacts. Due to the computational complexity of mobility control, it is challenging to assess or compare alternative policies. Here, we develop a pandemic policy assessment system that employs artificial intelligence (AI) to evaluate and analyze mobility-control policies. The system includes three components: (1) a general simulation framework that models different policies to comparable network-flow control problems; (2) a reinforcement-learning (RL) oracle to explore the upper-bound execution results of policies; and (3) comprehensive protocols for converting the RL results to policy-assessment measures, including execution complexity, effectiveness, cost and benefit, and risk. We applied the system to real-world metropolitan data and evaluated three popular policies: city lockdown, community quarantine, and route management. For each policy, we generated mobility-pandemic trade-off frontiers. The results manifest that the smartest policies, such as route management, have high execution complexity but limited additional gain from mobility retention. In contrast, a moderate-level intelligent policy such as community quarantine has acceptable execution complexity but can effectively suppress infections and largely mitigate mobility interventions. The frontiers also show one or two turning points, reflecting the safe threshold of mobility retention when considering policy-execution errors. In addition, we simulated different policy environments and found inspirations for the current policy debates on the zero-COVID policy, vaccination policy, and relaxing restrictions.Entities:
Mesh:
Year: 2022 PMID: 35974068 PMCID: PMC9379881 DOI: 10.1038/s41598-022-17892-8
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.996
Figure 1Workflow and components of the proposed AI-powered policy assessment system.
Figure 2(a) Urban interregional mobility. (b) The modeling for pandemic transmission via mobility. (c) The modeling of interregional mobility control.
Figure 3(a)/(b) The control extents and pandemic statistics of two example policies that react differently according to different given health care resources; Mobility* refers to the smoothed mobility. (c) Dynamic mobility restrictions of city lockdown with high health care resources in the early stage, mid-stage, and late stage of the pandemic; for each stage, we demonstrate control actions in three example days. (d) The trade-off relationship between mobility retention and infection suppression.
Figure 4Ideally executing community quarantine and route management requires “community collaboration”. (a) Intuitive explanation. (b) The control extents and pandemic statistics of example communities; one community would accept risky mobility from another community to relieve its lockdown pressure; in the meantime, it would lock itself down to prevent further pandemic spread. (c) The Pearson correlation coefficient between the mobility of every region and its collaborative neighbor; for the example two communities, the coefficient is . (d) The overall control extents and pandemic statistics of the city.
Figure 5The cost-benefit relationship between mobility retention and pandemic suppression.
Statistical comparison of the complexity of city lockdown, community quarantine, and route management.
| Policy | Action count | Daily action std |
|---|---|---|
| City lockdown | 1 | 0.05 |
| Community quarantine | 323 | 0.38 |
| Route management | 16,285 | 0.36 |
The computation of daily action Std is detailed in “Experiment settings” section.
Figure 6The city lockdown policy reacts differently to different vaccination settings. For both settings, the speed of vaccination is set as 0.5% of the population per day. (a) Start vaccination when the total infection rate reaches 15%. (b) Start vaccination when the total infection rate reaches 10%.
The summary of pandemic-related notations.
| Term/notation | Definition |
|---|---|
| Superscript | At time step |
| Subscript | At region |
| Subscript | Visible pandemic state |
| The total population | |
| The number of susceptible population | |
| The number of infected but not identified/hospitalized population | |
| The number of hospitalized population | |
| The number of recovered population | |
The summary of mobility-related notations.
| Term/notation | Definition |
|---|---|
| Superscript | At time step |
| Subscript | The original demand without restrictions |
| Subscript | With restriction |
| Subscript | Region index |
| The mobility. A matrix | |
| The OD flow from | |
Subscript can be either d or p.
The summary of the prolonged dataset.
| City | Regions | Mean population | Duration | |
|---|---|---|---|---|
| Beijing | 1686 | 0.18 | 744 Days |
counts the mean probability for an individual to move in 1 h.