Literature DB >> 3597394

Skeletal muscle phosphorylase kinase catalytic subunit mRNAs are expressed in heart tissue but not in liver.

P K Bender, C P Emerson.   

Abstract

A cDNA encoding the skeletal muscle phosphorylase kinase catalytic subunit gamma has been isolated and sequenced. It contains 57 nucleotides of 5' nontranslated sequence, the entire coding sequence, and 1004 nucleotides of 3' nontranslated sequence. Probes derived from this gamma-cDNA were used to investigate the expression of gamma-messages in liver, heart, and skeletal muscle tissues. The results demonstrate that the gamma-mRNAs expressed in heart tissue are homologous to the skeletal muscle gamma-mRNAs. However, in liver tissue, no homologous gamma-mRNAs were detected. The implications of these results for understanding gamma-isoform expression and the possibility of a liver-specific gamma-gene are discussed.

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Year:  1987        PMID： 3597394

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  14 in total

Review 1.  Molecular genetics of phosphorylase kinase: cDNA cloning, chromosomal mapping and isoform structure.

Authors:  M W Kilimann
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

Review 2.  Phosphorylase b kinase deficiency in man: a review.

Authors:  I E Van den Berg; R Berger
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

Review 3.  Genetic deficiencies of the glycogen phosphorylase system.

Authors:  J Hendrickx; P J Willems
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

4.  The association of phosphorylase kinase with membranes of rat liver smooth endoplasmic reticulum.

Authors:  G A Maridakis; T G Sotiroudis
Journal:  Mol Cell Biochem       Date:  1996-01-26       Impact factor: 3.396

5.  I/Lyn mouse phosphorylase kinase deficiency: mutation disrupts expression of the alpha/alpha'-subunit mRNAs.

Authors:  P K Bender; P A Lalley
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

6.  Nucleotide sequence of cDNA encoding the catalytic subunit of phosphorylase kinase from rat soleus muscle.

Authors:  K C Cawley; C Ramachandran; F A Gorin; D A Walsh
Journal:  Nucleic Acids Res       Date:  1988-03-25       Impact factor: 16.971

7.  cDNA cloning and complete primary structure of skeletal muscle phosphorylase kinase (alpha subunit).

Authors:  N F Zander; H E Meyer; E Hoffmann-Posorske; J W Crabb; L M Heilmeyer; M W Kilimann
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

8.  Baculovirus-directed expression of the gamma-subunit of phosphorylase kinase: purification and calmodulin dependence.

Authors:  R A Lanciotti; P K Bender
Journal:  Biochem J       Date:  1994-04-01       Impact factor: 3.857

Review 9.  Fatal infantile hypertrophic cardiomyopathy secondary to deficiency of heart specific phosphorylase b kinase.

Authors:  M Elleder; Y S Shin; A Zuntová; P Vojtovic; V Chalupecký
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1993

10.  DPhK-gamma, a putative Drosophila kinase with homology to vertebrate phosphorylase kinase gamma subunits: molecular characterisation of the gene and phenotypic analysis of loss of function mutants.

Authors:  S M Bahri; W Chia
Journal:  Mol Gen Genet       Date:  1994-12-01
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