| Literature DB >> 3596903 |
G Vertuani, S Spisani, M Boggian, S Traniello, A Scatturin.
Abstract
The conformational behavior of the chemotactic peptide analogs formylmethionylleucylphenylalanine methyl ester (CHO-Met-Leu-Phe-OMe) and formylmethionylleucylcyclohexylalanine methyl ester (CHO-Met-Leu-Cha-OMe) has been studied in solvents of different polarity by circular dichroism and infrared absorption. Both analogs and very probably the chemotactic peptide formylmethionylleucylphenylalanine (CHO-Met-Leu-Phe-OH) preferably adopt in solution a folded "active" conformation which allows a strong interaction with the receptor on the human polymorphonuclear leukocyte surface.Entities:
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Year: 1987 PMID： 3596903 DOI： 10.1111/j.1399-3011.1987.tb02280.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377