Literature DB >> 35968796

Stem Cell Therapy for Repair of the Injured Brain: Five Principles.

Ruslan Rust1,2, Christian Tackenberg1,2.   

Abstract

Cell therapy holds great promise for regenerative treatment of disease. Despite recent breakthroughs in clinical research, applications of cell therapies to the injured brain have not yielded the desired results. We pinpoint current limitations and suggest five principles to advance stem cell therapies for brain regeneration. While we focus on cell therapy for stroke, all principles also apply for other brain diseases.

Entities:  

Keywords:  NPCs; brain injury; cell therapy; iPSCs; regenerative therapy; stroke

Year:  2022        PMID： 35968796     DOI： 10.1177/10738584221110100

Source DB:  PubMed          Journal:  Neuroscientist        ISSN： 1073-8584            Impact factor:   7.235


  2 in total

1.  Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications.

Authors:  Ruslan Rust; Rebecca Z Weber; Melanie Generali; Debora Kehl; Chantal Bodenmann; Daniela Uhr; Debora Wanner; Kathrin J Zürcher; Hirohide Saito; Simon P Hoerstrup; Roger M Nitsch; Christian Tackenberg
Journal:  J Transl Med       Date:  2022-09-16       Impact factor: 8.440

2.  Deep learning-based behavioral profiling of rodent stroke recovery.

Authors:  Christian Tackenberg; Ruslan Rust; Rebecca Z Weber; Geertje Mulders; Julia Kaiser
Journal:  BMC Biol       Date:  2022-10-15       Impact factor: 7.364
  2 in total

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