Sushant S Mane1, Jyothi Janardhanan1, Manas Pustake2, Akshay Wanvat1, Gazi Israil Khan1, Rajratna Chopade1. 1. Centre of Excellence for Pediatric TB and Department of Pediatrics, Grant Government Medical College and Sir JJ Group of Hospitals, Byculla, Mumbai, Maharashtra. 2. Centre of Excellence for Pediatric TB and Department of Pediatrics, Grant Government Medical College and Sir JJ Group of Hospitals, Byculla, Mumbai, Maharashtra. Correspondence to: Dr Manas Pustake, Centre of Excellence for Pediatric TB, Grant Government Medical College and Sir JJ Group of Hospitals, Byculla, Mumbai, Maharashtra. pustakemanas@gmail.com.
Abstract
OBJECTIVE: To evaluate the outcome of Coronavirus disease 2019 (COVID-19) infection in children and adolescents with tuberculosis. METHODS: We analyzed hospital records for the period May, 2020 to September, 2021 for children who were severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) positive or SARS-CoV-2 antibody positive. They were divided into two groups viz., those with tuberculosis (tuberculosis group) and those without tuberculosis (non-TB group). Demographic information, symptoms, and outcomes of COVID-19 were compared between the two groups. RESULTS: Median (IQR) age of participants was 11 (8,14) and 4.5 (2,9) year for the tuberculosis and non-TB groups, respectively. 93.5% and 36.1% of children were asymptomatic in the tuberculosis and non-TB group, respectively. No variable in the study was significantly associated with COVID-19 positivity in children with tuberculosis. No difference was found in the outcomes of COVID-19 infection in children having tuberculosis. CONCLUSIONS: No differences were noted in the outcomes of COVID-19 infection in children having tuberculosis.
OBJECTIVE: To evaluate the outcome of Coronavirus disease 2019 (COVID-19) infection in children and adolescents with tuberculosis. METHODS: We analyzed hospital records for the period May, 2020 to September, 2021 for children who were severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) positive or SARS-CoV-2 antibody positive. They were divided into two groups viz., those with tuberculosis (tuberculosis group) and those without tuberculosis (non-TB group). Demographic information, symptoms, and outcomes of COVID-19 were compared between the two groups. RESULTS: Median (IQR) age of participants was 11 (8,14) and 4.5 (2,9) year for the tuberculosis and non-TB groups, respectively. 93.5% and 36.1% of children were asymptomatic in the tuberculosis and non-TB group, respectively. No variable in the study was significantly associated with COVID-19 positivity in children with tuberculosis. No difference was found in the outcomes of COVID-19 infection in children having tuberculosis. CONCLUSIONS: No differences were noted in the outcomes of COVID-19 infection in children having tuberculosis.
Authors: C Liu; Y Yu; J Fleming; T Wang; S Shen; Y Wang; L Fan; J Ma; Y Gu; Y Chen Journal: Int J Tuberc Lung Dis Date: 2020-07-01 Impact factor: 2.373
Authors: Jeremiah Chakaya; Mishal Khan; Francine Ntoumi; Eleni Aklillu; Razia Fatima; Peter Mwaba; Nathan Kapata; Sayoki Mfinanga; Seyed Ehtesham Hasnain; Patrick D M C Katoto; André N H Bulabula; Nadia A Sam-Agudu; Jean B Nachega; Simon Tiberi; Timothy D McHugh; Ibrahim Abubakar; Alimuddin Zumla Journal: Int J Infect Dis Date: 2021-03-11 Impact factor: 3.623