Literature DB >> 35962265

Forecasting the Potential Effects of Climate Change on Malaria in the Lake Victoria Basin Using Regionalized Climate Projections.

Ednah N Ototo1,2, Joseph O Ogutu3, Andrew Githeko2, Mohammed Y Said4,5, Lucy Kamau1, Didacus Namanya6, Stella Simiyu4, Stephen Mutimba4.   

Abstract

BACKGROUND: Malaria epidemics are increasing in East Africa since the 1980s, coincident with rising temperature and widening climate variability. A projected 1-3.5 °C rise in average global temperatures by 2100 could exacerbate the epidemics by modifying disease transmission thresholds. Future malaria scenarios for the Lake Victoria Basin (LVB) are quantified for projected climate scenarios spanning 2006-2100.
METHODS: Regression relationships are established between historical (1995-2010) clinical malaria and anaemia cases and rainfall and temperature for four East African malaria hotspots. The vector autoregressive moving average processes model, VARMAX (p,q,s), is then used to forecast malaria and anaemia responses to rainfall and temperatures projected with an ensemble of eight General Circulation Models (GCMs) for climate change scenarios defined by three Representative Concentration Pathways (RCPs 2.6, 4.5 and 8.5).
RESULTS: Maximum temperatures in the long rainy (March-May) and dry (June-September) seasons will likely increase by over 2.0 °C by 2070, relative to 1971-2000, under RCPs 4.5 and 8.5. Minimum temperatures (June-September) will likely increase by over 1.5-3.0 °C under RCPs 2.6, 4.5 and 8.5. The short rains (OND) will likely increase more than the long rains (MAM) by the 2050s and 2070s under RCPs 4.5 and 8.5. Historical malaria cases are positively and linearly related to the 3-6-month running means of monthly rainfall and maximum temperature. Marked variation characterizes the patterns projected for each of the three scenarios across the eight General Circulation Models, reaffirming the importance of using an ensemble of models for projections.
CONCLUSIONS: The short rains (OND), wet season (MAM) temperatures and clinical malaria cases will likely increase in the Lake Victoria Basin. Climate change adaptation and mitigation strategies, including malaria control interventions could reduce the projected epidemics and cases. Interventions should reduce emerging risks, human vulnerability and environmental suitability for malaria transmission.
© 2022. The Author(s).

Entities:  

Keywords:  Climate change; Malaria; Regionalized climate projections

Year:  2022        PMID: 35962265     DOI: 10.1007/s11686-022-00588-4

Source DB:  PubMed          Journal:  Acta Parasitol        ISSN: 1230-2821            Impact factor:   1.534


  36 in total

Review 1.  Mixed picture for changes in stable malaria distribution with future climate in Africa.

Authors:  Christopher J Thomas; Gemma Davies; Christine E Dunn
Journal:  Trends Parasitol       Date:  2004-05

2.  Climatic, socio-economic, and health factors affecting human vulnerability to cholera in the Lake Victoria basin, East Africa.

Authors:  Daniel Olago; Michael Marshall; Shem O Wandiga; Maggie Opondo; Pius Z Yanda; Richard Kanalawe; Andrew K Githeko; Tim Downs; Alfred Opere; Robert Kavumvuli; Edward Kirumira; Laban Ogallo; Paul Mugambi; Eugene Apindi; Faith Githui; James Kathuri; Lydia Olaka; Rehema Sigalla; Robinah Nanyunja; Timothy Baguma; Pius Achola
Journal:  Ambio       Date:  2007-06       Impact factor: 5.129

3.  Optimal temperature for malaria transmission is dramatically lower than previously predicted.

Authors:  Erin A Mordecai; Krijn P Paaijmans; Leah R Johnson; Christian Balzer; Tal Ben-Horin; Emily de Moor; Amy McNally; Samraat Pawar; Sadie J Ryan; Thomas C Smith; Kevin D Lafferty
Journal:  Ecol Lett       Date:  2012-10-11       Impact factor: 9.492

4.  Malaria resurgence in the East African highlands: temperature trends revisited.

Authors:  M Pascual; J A Ahumada; L F Chaves; X Rodó; M Bouma
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-29       Impact factor: 11.205

5.  Burden of climate change on malaria mortality.

Authors:  Shouro Dasgupta
Journal:  Int J Hyg Environ Health       Date:  2018-04-20       Impact factor: 5.840

6.  Surveillance of vector populations and malaria transmission during the 2009/10 El Niño event in the western Kenya highlands: opportunities for early detection of malaria hyper-transmission.

Authors:  Ednah N Ototo; Andrew K Githeko; Christine L Wanjala; Thomas W Scott
Journal:  Parasit Vectors       Date:  2011-07-22       Impact factor: 3.876

7.  Mapping Physiological Suitability Limits for Malaria in Africa Under Climate Change.

Authors:  Sadie J Ryan; Amy McNally; Leah R Johnson; Erin A Mordecai; Tal Ben-Horin; Krijn Paaijmans; Kevin D Lafferty
Journal:  Vector Borne Zoonotic Dis       Date:  2015-11-18       Impact factor: 2.133

8.  Hot topic or hot air? Climate change and malaria resurgence in East African highlands.

Authors:  Simon I Hay; David J Rogers; Sarah E Randolph; David I Stern; Jonathan Cox; G Dennis Shanks; Robert W Snow
Journal:  Trends Parasitol       Date:  2002-12

9.  Malaria in East African highlands during the past 30 years: impact of environmental changes.

Authors:  Yousif E Himeidan; Eliningaya J Kweka
Journal:  Front Physiol       Date:  2012-08-02       Impact factor: 4.566

10.  Development and validation of climate and ecosystem-based early malaria epidemic prediction models in East Africa.

Authors:  Andrew K Githeko; Laban Ogallo; Martha Lemnge; Michael Okia; Ednah N Ototo
Journal:  Malar J       Date:  2014-08-22       Impact factor: 2.979

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