Literature DB >> 35958473

Clinical outcomes and risk factors for postoperative complications in children with Hirschsprung's disease.

Tingting Gao1, Weijue Xu1, Qingfeng Sheng1, Ting Xu1, Wei Wu1, Zhibao Lv1.   

Abstract

OBJECTIVE: To explore and analyze the risk factors for postoperative complications in patients with Hirschsprung's disease (HD).
METHODS: Patients with HD admitted to the hospital from 2015 to 2020 were reviewed in this retrospective study. Follow-up data collected included constipation, fecal incontinence, anastomotic fistula, Hirschsprung's-associated enterocolitis (HAEC), and readmission. The putative risk factors for postoperative complications in patients with HD were as follows: clinical classification, gender, operative age, hemoglobin and serum albumin levels and preoperative HAEC. A follow-up survey was conducted for all patients by telephone. Data were analyzed statistically using SPSS version 23.0.
RESULTS: A total of 154 patients were included in the study, of whom 119 patients were followed up successfully. 53 patients who had complications postoperatively were compared to 66 patients who had no related complications. Among patients with complications: 8 had constipation, 22 had fecal incontinence and 33 had HAEC. The gender, operative age, hemoglobin levels and preoperative HAEC did not differ significantly between the two groups. However, significant differences were observed between the 2 groups in clinical classification, surgical method, serum albumin level, and whether or not a one-stage operation was performed (P<0.05).
CONCLUSION: Clinical classification, surgical method, preoperative albumin level and whether or not a one-stage operation was performed emerged as risk factors affecting the postoperative complications of patients with HD. Therefore, the prognosis in HD can be improved by strengthening the preoperative nutritional support and selecting appropriate surgical methods according to the clinical subtype. AJTR
Copyright © 2022.

Entities:  

Keywords:  Hirschsprung’s disease; Hirschsprung’s-associated enterocolitis; complications; risk factors; surgery

Year:  2022        PMID: 35958473      PMCID: PMC9360846     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   3.940


  29 in total

Review 1.  Guidelines for synoptic reporting of surgery and pathology in Hirschsprung disease.

Authors:  Laura V Veras; Michael Arnold; Jeffrey R Avansino; Kevin Bove; Robert A Cowles; Megan M Durham; Allan M Goldstein; Chandra Krishnan; Jacob C Langer; Marc Levitt; Hector Monforte-Munoz; Raja Rabah; Miguel Reyes-Mugica; Michael D Rollins; Raj P Kapur; Ankush Gosain
Journal:  J Pediatr Surg       Date:  2019-03-21       Impact factor: 2.545

2.  Factors influencing the incidence of Hirschsprung associated enterocolitis (HAEC).

Authors:  Annie Le-Nguyen; Franziska Righini-Grunder; Nelson Piché; Christophe Faure; Ann Aspirot
Journal:  J Pediatr Surg       Date:  2019-01-31       Impact factor: 2.545

3.  Comparison of Hirschsprung-associated enterocolitis following Soave and Duhamel procedures.

Authors:  Isidora Galuh Parahita; Akhmad Makhmudi
Journal:  J Pediatr Surg       Date:  2017-07-17       Impact factor: 2.545

4.  A population-based, complete follow-up of 146 consecutive patients after transanal mucosectomy for Hirschsprung disease.

Authors:  Malla I Neuvonen; Kristiina Kyrklund; Harry G Lindahl; Antti I Koivusalo; Risto J Rintala; Mikko P Pakarinen
Journal:  J Pediatr Surg       Date:  2015-02-14       Impact factor: 2.545

5.  Functional outcome after operation for Hirschsprung disease--transanal vs transabdominal approach.

Authors:  Kjetil Juul Stensrud; Ragnhild Emblem; Kristin Bjørnland
Journal:  J Pediatr Surg       Date:  2010-08       Impact factor: 2.545

Review 6.  Probiotics for the prevention of Hirschsprung-associated enterocolitis.

Authors:  Fan Mei; Mei Wu; Li Zhao; Kaiyan Hu; Qianqian Gao; Fei Chen; Joey Sw Kwong; Yanan Wang; Xi Ping Shen; Bin Ma
Journal:  Cochrane Database Syst Rev       Date:  2022-04-26

7.  Damaged anal canal as a cause of fecal incontinence after surgical repair for Hirschsprung disease - a preventable and under-reported complication.

Authors:  Andrea Bischoff; Jason Frischer; Jennifer Leslie Knod; Belinda Dickie; Marc A Levitt; Monica Holder; Lyndsey Jackson; Alberto Peña
Journal:  J Pediatr Surg       Date:  2016-09-04       Impact factor: 2.545

Review 8.  Functional outcome, quality of life, and 'failures' following pull-through surgery for hirschsprung's disease: A review of practice at a single-center.

Authors:  Oliver G Townley; Richard M Lindley; Marta C Cohen; Govind V Murthi
Journal:  J Pediatr Surg       Date:  2019-11-05       Impact factor: 2.545

Review 9.  Long-term results of transanal pull-through for Hirschsprung's disease: a meta-analysis.

Authors:  J Zimmer; C Tomuschat; P Puri
Journal:  Pediatr Surg Int       Date:  2016-07-06       Impact factor: 1.827

10.  Long-term outcomes and quality of life of patients with Hirschsprung disease: a systematic review and meta-analysis.

Authors:  Ying Dai; Yongfang Deng; Yan Lin; Runxian Ouyang; Le Li
Journal:  BMC Gastroenterol       Date:  2020-03-12       Impact factor: 3.067

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