Literature DB >> 35958451

The value of umbilical artery blood gas analysis in the diagnosis and prognosis evaluation of fetal distress.

Yu Cai1, Xiaojuan Zhang1, Xiaozhi Wu1, Honglan Liu1, Lianfeng Qi1, Xiaoyun Liu1.   

Abstract

To explore the diagnostic specificity and clinical application of neonatal umbilical cord blood gas analysis in the prognosis of fetal distress, and to provide theoretical basis for neonatal rescue. Clinical data of a total of 240 singleton pregnant women and their neonates who delivered in the Obstetrics Department of our hospital from January 2021 to December 2021 were retrospectively analyzed. The pregnant women and their newborns were divided into an acute group (acute fetal distress), a chronic group (chronic fetal distress) and a control group (no fetus distress), with 80 cases in each. The umbilical artery blood gas analysis values including power of hydrogen (PH), partial pressure of carbon dioxide (PCO2), partial pressure of oxygen (PO2), bicarbonate radical (HCO3 -), buffer excess (BE) and the Apgar score, as well as the neonatal asphyxia outcome after birth were recorded. There were statistically significant differences in fetal condition, PH and BE between newborns with asphyxia and normal newborns (P<0.05). The incidence of neonatal distress was 1.25% in the control group and 19.38% in the fetal distress group (including acute and chronic groups). Logistic regression analysis found that fetal distress was a risk factor for neonatal asphyxia (Odds Ratio (OR)=11.064, P=0.012). The specificity and sensitivity of neonatal cord blood gas analysis in diagnosing neonatal asphyxia were 95.69% and 80.65%, respectively. The specificity of Apgar score in the diagnosis of neonatal asphyxia was 94.74%, and the sensitivity was 70.97%. The rate of neonatal asphyxia in the chronic fetal distress group (26.25%) was higher than that in the acute fetal distress group (12.5%). The proportion of neonatal severe asphyxia in the chronic fetal distress group (66.67%) was higher than that in the acute group (20%). The PH and BE levels in the chronic fetal distress group were lower than those in the control group and acute fetal distress group (P<0.05). Cord blood gas analysis can help to improve the accuracy of fetal distress diagnosis. Cord blood gas is closely related to neonatal prognosis. Compared with acute fetal distress, chronic fetal distress is more likely to lead to neonatal acidosis and asphyxia. AJTR
Copyright © 2022.

Entities:  

Keywords:  Umbilical artery blood gas analysis; diagnosis; fetal distress; prognosis

Year:  2022        PMID: 35958451      PMCID: PMC9360831     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   3.940


  24 in total

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Journal:  BJOG       Date:  2019-12-17       Impact factor: 6.531

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Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2013-01

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Authors:  Mehreen Zaigham; Sara Helfer; Karl Heby Kristensen; Per-Erik Isberg; Nana Wiberg
Journal:  Acta Obstet Gynecol Scand       Date:  2020-06-19       Impact factor: 3.636

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Authors:  Susanne Hvolgaard Mikkelsen; Jørn Olsen; Bodil Hammer Bech; Chunsen Wu; Zeyan Liew; Mika Gissler; Carsten Obel; Onyebuchi Arah
Journal:  Acta Paediatr       Date:  2017-04-17       Impact factor: 2.299

6.  Apgar score in premature infants associated with neonatal death prediction.

Authors:  Mehreen Zaigham; Karel Maršál
Journal:  J Pediatr       Date:  2020-10-22       Impact factor: 4.406

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Authors:  Graeme R Polglase; Tracey Ong; Noah H Hillman
Journal:  Clin Perinatol       Date:  2016-06-22       Impact factor: 3.430

8.  Apgar Score and Risk of Neonatal Death among Preterm Infants.

Authors:  Sven Cnattingius; Stefan Johansson; Neda Razaz
Journal:  N Engl J Med       Date:  2020-07-02       Impact factor: 91.245

9.  Clinico-Biochemical Correlation in Birth Asphyxia and Its Effects on Outcome.

Authors:  Abhilipsa Acharya; Banashree Swain; Sarbeswar Pradhan; Pradeep K Jena; Nirmal K Mohakud; Arakhita Swain; Niranjan Mohanty
Journal:  Cureus       Date:  2020-11-09

10.  Factors Associated with Apgar Score among Newborns Delivered by Cesarean Sections at Gandhi Memorial Hospital, Addis Ababa.

Authors:  Mohammed Suleiman Obsa; Getahun Molla Shanka; Misrak Woldayohannes Menchamo; Robera Olana Fite; Meron Abrar Awol
Journal:  J Pregnancy       Date:  2020-01-06
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