Literature DB >> 35957945

Practice-Changing Perspectives regarding Systemic Therapy in Early Breast Cancer: Opinions of German Experts regarding the 17th St. Gallen International Consensus Conference.

Cornelia Kolberg-Liedtke1,2,3, Diana Lüftner4, Sara Y Brucker5, Wilfried Budach6, Carsten Denkert7, Peter A Fasching8, Renate Haidinger9, Nadia Harbeck10, Jens Huober11, Christian Jackisch12, Wolfgang Janni13, David Krug14, Thorsten Kühn15, Sibylle Loibl16,17, Volkmar Müller18, Andreas Schneeweiss19, Christoph Thomssen20, Michael Untch21, Marc Thill22.   

Abstract

The general topic of this year's 17th St. Gallen (SG) International Consensus Conference on the treatment of patients with early breast cancer (SG-BCC) was "Customizing local and systemic therapies for women with early breast cancer." This topic considers that each treatment decision must also consider the cancer-specific situation of the individual patient. This year, the votes of the SG-BCC were again discussed taking into account the multidisciplinary German S3 Guidelines and the recommendations of the Breast Cancer Working Group of the AGO (Arbeitsgemeinschaft Gynäkologische Onkologie; AGO Mamma). As the international panel of the SG-BCC consists of experts from different countries, the votes do represent an international cross-section of opinions. Therefore, it is useful to discuss the voting results with respect to the German evidence-based treatment guidelines. This publication focuses mainly on systemic treatment.
Copyright © 2022 by S. Karger AG, Basel.

Entities:  

Keywords:  (Neo)adjuvant systemic treatment; Early breast cancer; St. Gallen Consensus 2021; Targeted therapy

Year:  2022        PMID： 35957945      PMCID： PMC9247526          DOI： 10.1159/000517501

Source DB:  PubMed          Journal:  Breast Care (Basel)        ISSN： 1661-3791            Impact factor:   2.268


  17 in total

1.  Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast Cancer: The SCALP Randomized Clinical Trial.

Authors:  Julie Nangia; Tao Wang; Cynthia Osborne; Polly Niravath; Kristen Otte; Steven Papish; Frankie Holmes; Jame Abraham; Mario Lacouture; Jay Courtright; Richard Paxman; Mari Rude; Susan Hilsenbeck; C Kent Osborne; Mothaffar Rimawi
Journal:  JAMA       Date:  2017-02-14       Impact factor: 56.272

2.  Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.

Authors:  Gunter von Minckwitz; Marion Procter; Evandro de Azambuja; Dimitrios Zardavas; Mark Benyunes; Giuseppe Viale; Thomas Suter; Amal Arahmani; Nathalie Rouchet; Emma Clark; Adam Knott; Istvan Lang; Christelle Levy; Denise A Yardley; Jose Bines; Richard D Gelber; Martine Piccart; Jose Baselga
Journal:  N Engl J Med       Date:  2017-06-05       Impact factor: 91.245

3.  Scalp Hypothermia for Preventing Alopecia During Chemotherapy. A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Hope S Rugo; Jeffrey Voigt
Journal:  Clin Breast Cancer       Date:  2017-08-10       Impact factor: 3.225

4.  Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for Research and Treatment of Cancer trial 10902.

Authors:  J A van der Hage; C J van de Velde; J P Julien; M Tubiana-Hulin; C Vandervelden; L Duchateau
Journal:  J Clin Oncol       Date:  2001-11-15       Impact factor: 44.544

5.  Effect of preoperative chemotherapy on the outcome of women with operable breast cancer.

Authors:  B Fisher; J Bryant; N Wolmark; E Mamounas; A Brown; E R Fisher; D L Wickerham; M Begovic; A DeCillis; A Robidoux; R G Margolese; A B Cruz; J L Hoehn; A W Lees; N V Dimitrov; H D Bear
Journal:  J Clin Oncol       Date:  1998-08       Impact factor: 44.544

6.  Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.

Authors:  Joseph A Sparano; Robert J Gray; Della F Makower; Kathleen I Pritchard; Kathy S Albain; Daniel F Hayes; Charles E Geyer; Elizabeth C Dees; Edith A Perez; John A Olson; JoAnne Zujewski; Tracy Lively; Sunil S Badve; Thomas J Saphner; Lynne I Wagner; Timothy J Whelan; Matthew J Ellis; Soonmyung Paik; William C Wood; Peter Ravdin; Maccon M Keane; Henry L Gomez Moreno; Pavan S Reddy; Timothy F Goggins; Ingrid A Mayer; Adam M Brufsky; Deborah L Toppmeyer; Virginia G Kaklamani; James N Atkins; Jeffrey L Berenberg; George W Sledge
Journal:  N Engl J Med       Date:  2015-09-27       Impact factor: 91.245

7.  COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy for early breast cancer.

Authors:  Katharina Smetanay; Philippe Junio; Manuel Feißt; Julia Seitz; Jessica Cecile Hassel; Luisa Mayer; Lina Maria Matthies; Arina Schumann; André Hennigs; Jörg Heil; Christof Sohn; Dirk Jaeger; Andreas Schneeweiss; Frederik Marmé
Journal:  Breast Cancer Res Treat       Date:  2018-09-25       Impact factor: 4.872

Review 8.  AGO Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2021.

Authors:  Nina Ditsch; Cornelia Kolberg-Liedtke; Michael Friedrich; Christian Jackisch; Ute-Susann Albert; Maggie Banys-Paluchowski; Ingo Bauerfeind; Jens-Uwe Blohmer; Wilfried Budach; Peter Dall; Eva M Fallenberg; Peter A Fasching; Tanja Fehm; Bernd Gerber; Oleg Gluz; Nadia Harbeck; Jörg Heil; Jens Huober; Hans-Heinrich Kreipe; David Krug; Thorsten Kühn; Sherko Kümmel; Sibylle Loibl; Diana Lüftner; Michael P Lux; Nicolai Maass; Christoph Mundhenke; Ulrike Nitz; Tjoung-Won Park-Simon; Toralf Reimer; Kerstin Rhiem; Achim Rody; Marcus Schmidt; Andreas Schneeweiss; Florian Schütz; Hans-Peter Sinn; Christine Solbach; Erich-Franz Solomayer; Elmar Stickeler; Christoph Thomssen; Michael Untch; Isabell Witzel; Achim Wöckel; Volkmar Müller; Wolfgang Janni; Marc Thill
Journal:  Breast Care (Basel)       Date:  2021-06-01       Impact factor: 2.268

9.  Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-group, randomised, phase 3 trial.

Authors:  Ian Smith; John Robertson; Lucy Kilburn; Maggie Wilcox; Abigail Evans; Chris Holcombe; Kieran Horgan; Cliona Kirwan; Elizabeth Mallon; Mark Sibbering; Anthony Skene; Raghavan Vidya; Maggie Cheang; Jane Banerji; James Morden; Kally Sidhu; Andrew Dodson; Judith M Bliss; Mitch Dowsett
Journal:  Lancet Oncol       Date:  2020-11       Impact factor: 41.316

Review 10.  Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials.

Authors: 
Journal:  Lancet Oncol       Date:  2017-12-11       Impact factor: 41.316
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