| Literature DB >> 3595791 |
Abstract
Electrophysiological experiments demonstrate that triiodothyronine (T3) exerts a direct effect on the membrane of a strain of cultured rat pituitary tumor cells, GH3/B6. These cells respond to pressure application of T3 (2-5 nl, concentration 1 X 10(-10) M) with an increase in the membrane resistance (Rm) and a hyperpolarization. Spontaneously firing cells become silent.Entities:
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Year: 1987 PMID: 3595791 DOI: 10.1007/bf02126342
Source DB: PubMed Journal: Experientia ISSN: 0014-4754