| Literature DB >> 35951296 |
Daniel G Cava1, Marisela Vélez2.
Abstract
Supported lipid bilayers (SLBs) are model membrane systems that can be used to study the interaction between amyloid fibers and membranes with atomic force microscopy (AFM). This chapter describes the preparation of SLBs on mica that can then be used as a substrate for fiber absorption. AFM can then be used to study the topography of the lipid-protein surface to study the evolution of the fibers, as well as the modifications on the membrane induced by their presence.Entities:
Keywords: Amyloid fibers; Atomic force microscope (AFM); Supported lipid bilayers (SLBs)
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Year: 2022 PMID： 35951296 DOI： 10.1007/978-1-0716-2529-3_8
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745