Yunus Erol Bozkurt1,2, Bilal H Gümüş3, Fatih Düzgün4, Nalan Neşe5. 1. Department of Urology, Celal Bayar University Faculty of Medicine, Manisa, Turkey. yunusbozkurt88@hotmail.com. 2. Department of Urology, Manisa Merkez Efendi State Hospital, Manisa, Turkey. yunusbozkurt88@hotmail.com. 3. Department of Urology, Celal Bayar University Faculty of Medicine, Manisa, Turkey. 4. Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey. 5. Department of Pathology, Celal Bayar University Faculty of Medicine, Manisa, Turkey.
Abstract
OBJECTIVE: Histopathological analysis of the relationship between penile elastography and erectile dysfunction. MATERIAL AND METHOD: 12 patients who applied to our clinic for erectile dysfunction in the last 1 year and accepted this study were included. Preoperative two-dimensional shear wave elastography imaging was performed in 12 patients and recorded in the Pascal (kPa) unit. Approximately 0.5 × 0.5 × 0.5 cm tissue samples were taken from the right and left cavernous tissue during penile prosthesis implantation operation. Tissue samples were sent to the pathology department. The percentage of the area covered by muscle fibers and elastic fibers in the corpus cavernosum was noted semi-quantitatively (ratio of muscle fibers and cavernous body elastic fiber score). All data obtained were compared with each other. RESULTS: Cavernous body elastic fiber score data(Grouped Score 1, 2 and 3) and percentage of cavernous body muscle fibers data (Grouped %10, %20, %30… %100) were compared with Shear wave elastography data (kPa). The results were not statistically significant according to the Kruskal Wallis Test. Cavernous body elastic fiber score and the percentage of cavernous body muscle fibers were also compared, it was not statistically significant according to the Kruskal Wallis test and Spearman's correlation test. CONCLUSIONS: Penile shear wave elastography can be used clinically to quantitatively assess the amount of smooth muscle cells and elastic fibers in the penis, but it deserves to be studied with a larger number of patients and a more specific interpretation of the pathology preparation.
OBJECTIVE: Histopathological analysis of the relationship between penile elastography and erectile dysfunction. MATERIAL AND METHOD: 12 patients who applied to our clinic for erectile dysfunction in the last 1 year and accepted this study were included. Preoperative two-dimensional shear wave elastography imaging was performed in 12 patients and recorded in the Pascal (kPa) unit. Approximately 0.5 × 0.5 × 0.5 cm tissue samples were taken from the right and left cavernous tissue during penile prosthesis implantation operation. Tissue samples were sent to the pathology department. The percentage of the area covered by muscle fibers and elastic fibers in the corpus cavernosum was noted semi-quantitatively (ratio of muscle fibers and cavernous body elastic fiber score). All data obtained were compared with each other. RESULTS: Cavernous body elastic fiber score data(Grouped Score 1, 2 and 3) and percentage of cavernous body muscle fibers data (Grouped %10, %20, %30… %100) were compared with Shear wave elastography data (kPa). The results were not statistically significant according to the Kruskal Wallis Test. Cavernous body elastic fiber score and the percentage of cavernous body muscle fibers were also compared, it was not statistically significant according to the Kruskal Wallis test and Spearman's correlation test. CONCLUSIONS: Penile shear wave elastography can be used clinically to quantitatively assess the amount of smooth muscle cells and elastic fibers in the penis, but it deserves to be studied with a larger number of patients and a more specific interpretation of the pathology preparation.
Authors: Selahittin Çayan; Muammer Kendirci; Önder Yaman; Ramazan Aşçı; İrfan Orhan; Mustafa Faruk Usta; Oğuz Ekmekçioğlu; Ateş Kadıoğlu Journal: Turk J Urol Date: 2017-06-01
Authors: Christian Gratzke; Javier Angulo; Kanchan Chitaley; Yu-Tian Dai; Noel N Kim; Jaw-Seung Paick; Ulf Simonsen; Stefan Uckert; Eric Wespes; Karl E Andersson; Tom F Lue; Christian G Stief Journal: J Sex Med Date: 2010-01 Impact factor: 3.802
Authors: Tsuyoshi Shiina; Kathryn R Nightingale; Mark L Palmeri; Timothy J Hall; Jeffrey C Bamber; Richard G Barr; Laurent Castera; Byung Ihn Choi; Yi-Hong Chou; David Cosgrove; Christoph F Dietrich; Hong Ding; Dominique Amy; Andre Farrokh; Giovanna Ferraioli; Carlo Filice; Mireen Friedrich-Rust; Kazutaka Nakashima; Fritz Schafer; Ioan Sporea; Shinichi Suzuki; Stephanie Wilson; Masatoshi Kudo Journal: Ultrasound Med Biol Date: 2015-03-21 Impact factor: 2.998
Authors: Alfredo Nicolosi; Edson D Moreira; Masafumi Shirai; Mohd Ismail Bin Mohd Tambi; Dale B Glasser Journal: Urology Date: 2003-01 Impact factor: 2.649