Shuman Tao1, Xiuyong Li2, Zhi Liu3, Youwei Bai4, Guangrong Qian5, Han Wu6, Ji Li7, Yuwen Guo8, Shanfei Yang9, Lei Chen10, Jian Yang11, Jiuhuai Han12, Shengyin Ma13, Jing Yang14, Linfei Yu15, Runzhi Shui16, Xiping Jin17, Hongyu Wang18, Fan Zhang19, Tianhao Chen20, Xinke Li21, Xiaoying Zong22, Li Liu23, Jihui Fan24, Wei Wang25, Yong Zhang26, Guangcai Shi27, Deguang Wang28. 1. Department of Nephrology, The Second Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China. 2. Blood Purification Center, No. 2 People's Hospital of Fuyang City, 1088 Yinghe West Road, Fuyang, 236015, China. 3. Department of Nephrology, The First Affiliated Hospital of Anhui University of Science & Technology, 203 Huaibin Road, Huainan, 232000, China. 4. Department of Nephrology, The Second People's Hospital of Lu'an City, 73 Mozitan Road , Lu'an, 237000, China. 5. Department of Nephrology, Maanshan People's Hospital, 45 Hubei Road, Maanshan, 243099, China. 6. Blood Purification Center, Bozhou People's Hospital, 616 Duzhong Road, Bozhou, 236814, China. 7. Department of Nephrology, Tongling People's Hospital, 468 Bijiashan Road, Tongling, 244099, China. 8. Department of Nephrology, Lujiang County People's Hospital, 32 Wenmingzhong Road, Lujiang, 231501, China. 9. Department of Nephrology, Northeast of the Intersection of Binyang Avenue and Dongjin Avenue, Shouxian County Hospital, Shouxian County, 232200, China. 10. Department of Nephrology, Hefei Jinnan Kidney Hospital, Northeast of the intersection of Fozhang Road and Beihai Road, Hefei, 230071, China. 11. Department of Nephrology, Funan County People's Hospital, 36 Santa Road, Funan County, 236300, China. 12. Department of Nephrology, Anqing Municipal Hospital, 87 East Tianzhushan Road, Anqing, 246003, China. 13. Department of Nephrology, Anhui Wanbei Coal-Electricity Group General Hospital, 125 Huaihe West Road, Suzhou, 234099, China. 14. Department of Nephrology, The First People's Hospital of Hefei, 390 Huaihe Road, Hefei, 230061, China. 15. Department of Nephrology, The People's Hospital of Taihu, 196 Renmin Road, Taihu County, 246400, China. 16. Blood Purification Center, Huangshan City People's Hospital, 4 Liyuan Road, Huangshan, 245000, China. 17. Department of Nephrology, Huainan Chao Yang Hospital, 15 Renmin South Road, Huainan, 232007, China. 18. Department of Nephrology, Lixin County People's Hospital, Intersection of Wenzhou Road and Feihe Road, Lixin County, 236700, China. 19. Department of Nephrology, Dongzhi County People's Hospital, 70 Jianshe Road, Dongzhi County, 247299, China. 20. Department of Nephrology, Tianchang City People's Hospital, 137 Jianshe East Road, Tianchang, 239399, China. 21. Department of Nephrology, Xiaoxian People's Hospital, 58 Jiankang Road, Xiaoxian County, 235200, China. 22. Department of Nephrology, The Second Affiliated Hospital of Bengbu Medical College, 633 Longhua Road, Bengbu, 233017, China. 23. Department of Nephrology, The Second People's Hospital of Hefei, 246 Heping Road, Hefei, 230012, China. 24. Department of Nephrology, Huaibei People's Hospital, 66 Huaihai West Road, Huaibei, 235000, China. 25. Department of Nephrology, The People's Hospital of Xuancheng City, 51 Dabatang Road, Xuancheng, 242099, China. 26. Department of Nephrology, Lujiang County Hospital of TCM, 350 Zhouyu Avenue, Lujiang County, 231501, China. 27. Department of Nephrology, The Fifth People's Hospital of Hefei, Yuxi Road, Hefei, 230011, China. 28. Department of Nephrology, The Second Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China. wangdeguang@ahmu.edu.cn.
Abstract
BACKGROUND: Chronic kidney disease-mineral bone disorder (CKD-MBD) is a common comorbidity in patients with CKD. The study aims to describe the control rates of serum-corrected calcium (Ca), phosphate (P) and intact parathyroid hormone (iPTH) and its risk factors among maintenance hemodialysis (MHD) patients in Anhui Province of China. METHODS: The study was conducted in 27 hemodialysis centers of Anhui Province between January 1st 2020 and December 31th 2020. Chi-square test was used to compare the control rates of serum-corrected Ca, P and iPTH between the present study and DOPPS 4 or Anhui Province in 2014. Binary logistic regression analysis was used to explore the risk factors of the control rates of serum-corrected Ca, P and iPTH. RESULTS: A total of 3 025 MHD patients were recruited in this study, with a mean age of 54.8 (SD: 12.8) years, and 60.1% were males. According to the Chinese Diagnosis and Treatment Guidelines for CKD-MBD, the control rates of serum-corrected Ca, P and iPTH in the present study were 57.9%, 20.0% and 56.0%, respectively. Based on KDOQI guidelines (2003), the control rates of the above indicators were 43.1%, 35.3% and 22.3%, respectively. The control rates of serum-corrected Ca, P and iPTH in this study were lower than those of DOPPS 4 (P < 0.001). Compared to the results of Anhui Province in 2014, the control rate of corrected Ca was higher (P < 0.001) and the control rate of iPTH was lower (P = 0.005). Age, residential area, BMI, dialysis vintage, albumin and hemoglobin levels were factors of serum-corrected Ca, P and iPTH not within target range. CONCLUSION: The control rates of serum-corrected Ca, P and iPTH in MHD patients in Anhui Province are relatively low. Monitoring and management should be strengthened to improve the prognosis of patients undergoing dialysis.
BACKGROUND: Chronic kidney disease-mineral bone disorder (CKD-MBD) is a common comorbidity in patients with CKD. The study aims to describe the control rates of serum-corrected calcium (Ca), phosphate (P) and intact parathyroid hormone (iPTH) and its risk factors among maintenance hemodialysis (MHD) patients in Anhui Province of China. METHODS: The study was conducted in 27 hemodialysis centers of Anhui Province between January 1st 2020 and December 31th 2020. Chi-square test was used to compare the control rates of serum-corrected Ca, P and iPTH between the present study and DOPPS 4 or Anhui Province in 2014. Binary logistic regression analysis was used to explore the risk factors of the control rates of serum-corrected Ca, P and iPTH. RESULTS: A total of 3 025 MHD patients were recruited in this study, with a mean age of 54.8 (SD: 12.8) years, and 60.1% were males. According to the Chinese Diagnosis and Treatment Guidelines for CKD-MBD, the control rates of serum-corrected Ca, P and iPTH in the present study were 57.9%, 20.0% and 56.0%, respectively. Based on KDOQI guidelines (2003), the control rates of the above indicators were 43.1%, 35.3% and 22.3%, respectively. The control rates of serum-corrected Ca, P and iPTH in this study were lower than those of DOPPS 4 (P < 0.001). Compared to the results of Anhui Province in 2014, the control rate of corrected Ca was higher (P < 0.001) and the control rate of iPTH was lower (P = 0.005). Age, residential area, BMI, dialysis vintage, albumin and hemoglobin levels were factors of serum-corrected Ca, P and iPTH not within target range. CONCLUSION: The control rates of serum-corrected Ca, P and iPTH in MHD patients in Anhui Province are relatively low. Monitoring and management should be strengthened to improve the prognosis of patients undergoing dialysis.
Authors: José Luis Fernández-Martín; Pablo Martínez-Camblor; María Paula Dionisi; Jürgen Floege; Markus Ketteler; Gérard London; Francesco Locatelli; José Luis Gorriz; Boleslaw Rutkowski; Aníbal Ferreira; Willem-Jan Bos; Adrian Covic; Minerva Rodríguez-García; José Emilio Sánchez; Diego Rodríguez-Puyol; Jorge B Cannata-Andia Journal: Nephrol Dial Transplant Date: 2015-04-28 Impact factor: 5.992
Authors: Claudia Lamina; Florian Kronenberg; Peter Stenvinkel; Marc Froissart; Lukas Forer; Sebastian Schönherr; David C Wheeler; Kai-Uwe Eckardt; Jürgen Floege Journal: Nephrol Dial Transplant Date: 2020-03-01 Impact factor: 5.992