Sahar Sobhani1, Saba Vakili2, Dina Javid Jam3, Reihaneh Aryan4, Majid Khadem-Rezaiyan5, Saeid Eslami6, Maryam Alinezhad-Namaghi7. 1. Department of Nursing and Midwifery Faculty of Nursing Gonabad University of Medical Sciences Gonabad Iran. 2. Medical Genetics Research Center Mashhad University of Medical Sciences Mashhad Iran. 3. Department of Clinical Biochemistry Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran. 4. Clinical Research Development Unit Imam Reza Hospital Mashhad University of Medical Sciences Mashhad Iran. 5. Clinical Research Development Unit Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran. 6. Department of Medical Informatics Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran. 7. Department of Nutrition Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.
Abstract
Background: Obesity and arteriosclerosis are both independently associated with cardiovascular disease risk. Obesity also may increase arterial stiffness. Aims: This study aimed to investigate the association between anthropometric indices and non-invasive arterial stiffness parameters, using data from a large population-based cohort of seemingly healthy women and men. Methods: A total of 5023 eligible participants were included in the study. The pulse wave velocity (PWV), central blood pressures, and bio-impedance measures were obtained at the time of enrollment. Multiple regression analysis was performed to assess the relationship between anthropometric indices with arterial stiffness parameters. Results: The mean age of participants was 45.3 ± 8.8 years, 2368 (47.1%) were males and 2655 (52.8%) were females. The prevalence of participant with underweight, normal weight, overweight, and obesity were 0.73%, 33.2%, 48.7%, and 17.2% respectively. Systolic and diastolic blood pressure, fatty liver, and hypertension were significantly higher in overweight/obesity participants. The overweight/obesity participants had significantly higher PWV than the normal-weight group (471.5 ± 42.6/496.7 ± 47.5 cm/s vs. 448.1 ± 41.4 cm/s, p < 0.001). Conclusion: The prevalence of diabetes, hypertension, fatty liver disease, chronic lung disease, and also kidney stones were significantly higher in overweight and individuals with obesity. Body mass index, body fat mass, waist-hip ratio abdominal circumference, neck circumference, visceral fat area, total body water, 50-kHz whole body phase angle are positively correlated with PWV. Augmentation index had no significant correlation with body mass index, arm, hip, and abdominal circumferences.
Background: Obesity and arteriosclerosis are both independently associated with cardiovascular disease risk. Obesity also may increase arterial stiffness. Aims: This study aimed to investigate the association between anthropometric indices and non-invasive arterial stiffness parameters, using data from a large population-based cohort of seemingly healthy women and men. Methods: A total of 5023 eligible participants were included in the study. The pulse wave velocity (PWV), central blood pressures, and bio-impedance measures were obtained at the time of enrollment. Multiple regression analysis was performed to assess the relationship between anthropometric indices with arterial stiffness parameters. Results: The mean age of participants was 45.3 ± 8.8 years, 2368 (47.1%) were males and 2655 (52.8%) were females. The prevalence of participant with underweight, normal weight, overweight, and obesity were 0.73%, 33.2%, 48.7%, and 17.2% respectively. Systolic and diastolic blood pressure, fatty liver, and hypertension were significantly higher in overweight/obesity participants. The overweight/obesity participants had significantly higher PWV than the normal-weight group (471.5 ± 42.6/496.7 ± 47.5 cm/s vs. 448.1 ± 41.4 cm/s, p < 0.001). Conclusion: The prevalence of diabetes, hypertension, fatty liver disease, chronic lung disease, and also kidney stones were significantly higher in overweight and individuals with obesity. Body mass index, body fat mass, waist-hip ratio abdominal circumference, neck circumference, visceral fat area, total body water, 50-kHz whole body phase angle are positively correlated with PWV. Augmentation index had no significant correlation with body mass index, arm, hip, and abdominal circumferences.
Authors: H K Chung; B Kang; J H Lee; J Y Shim; S Park; S-H Lee; Y K Park; E Park; N Chung; M-J Shin Journal: Nutr Metab Cardiovasc Dis Date: 2009-06-07 Impact factor: 4.222
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