Ana Lúcia Franco Ricardo1, Gabriel Araújo da Silva2, Celso Massahiro Ogawa1, Amanda D Nussi1, Catharina Simione De Rosa3, Jaqueline Serra Martins4, Sérgio Lúcio Pereira de Castro Lopes5, Simone Appenzeller4, Paulo Henrique Braz-Silva3, Andre Luiz Ferreira Costa6. 1. Postgraduate Program in Dentistry, Cruzeiro Do Sul University (UNICSUL), São Paulo, 01506-000, Brazil. 2. Division of Oral Radiology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Campinas, Brazil. 3. Department of Stomatology, School of Dentistry, University of São Paulo (USP), São Paulo, Brazil. 4. Rheumatology Department, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil. 5. Department of Diagnosis and Surgery, São José Dos Campos School of Dentistry, São Paulo State University (UNESP), São José dos Campos, SP, Brazil. 6. Postgraduate Program in Dentistry, Cruzeiro Do Sul University (UNICSUL), São Paulo, 01506-000, Brazil. alfcosta@gmail.com.
Abstract
OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects the joints and other organs, including the development of the former in a growing child. This study aimed to evaluate the feasibility of texture analysis (TA) based on magnetic resonance imaging (MRI) to provide biomarkers that serve to identify patients likely to progress to temporomandibular joint damage by associating JIA with age, gender and disease onset age. METHODS: The radiological database was retrospectively reviewed. A total of 45 patients were first divided into control group (23) and JIA group (22). TA was performed using grey-level co-occurrence matrix (GLCM) parameters, in which 11 textural parameters were calculated using MaZda software. These 11 parameters were ranked based on the p value obtained with ANOVA and then correlated with age, gender and disease onset age. RESULTS: Significant differences in texture parameters of condyle were demonstrated between JIA group and control group (p < 0.05). There was a progressive loss of uniformity in the grayscale pixels of MRI with an increasing age in JIA group. CONCLUSIONS: MRI TA of the condyle can make it possible to detect the alterations in bone marrow of patients with JIA and promising tool which may help the image analysis.
OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects the joints and other organs, including the development of the former in a growing child. This study aimed to evaluate the feasibility of texture analysis (TA) based on magnetic resonance imaging (MRI) to provide biomarkers that serve to identify patients likely to progress to temporomandibular joint damage by associating JIA with age, gender and disease onset age. METHODS: The radiological database was retrospectively reviewed. A total of 45 patients were first divided into control group (23) and JIA group (22). TA was performed using grey-level co-occurrence matrix (GLCM) parameters, in which 11 textural parameters were calculated using MaZda software. These 11 parameters were ranked based on the p value obtained with ANOVA and then correlated with age, gender and disease onset age. RESULTS: Significant differences in texture parameters of condyle were demonstrated between JIA group and control group (p < 0.05). There was a progressive loss of uniformity in the grayscale pixels of MRI with an increasing age in JIA group. CONCLUSIONS: MRI TA of the condyle can make it possible to detect the alterations in bone marrow of patients with JIA and promising tool which may help the image analysis.
Authors: Milena de Albuquerque; Lara G V Anjos; Helen Maia Tavares de Andrade; Márcia S de Oliveira; Gabriela Castellano; Thiago Junqueira Ribeiro de Rezende; Anamarli Nucci; Marcondes Cavalcante França Junior Journal: J Neuroimaging Date: 2015-05-25 Impact factor: 2.486
Authors: Matthew L Stoll; Anthony B P Morlandt; Suwat Teerawattanapong; Daniel Young; Peter D Waite; Randy Q Cron Journal: Rheumatology (Oxford) Date: 2012-12-05 Impact factor: 7.580