Literature DB >> 35948435

Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies!

Dorin-Bogdan Borza1, Pallavi Manral2.   

Abstract

Entities:  

Keywords:  anti-GBM disease; anti-hinge antibodies; endopeptidase therapy; imlifidase

Year:  2022        PMID: 35948435      PMCID: PMC9528323          DOI: 10.1681/ASN.2022050609

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN: 1046-6673            Impact factor:   14.978


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  5 in total

1.  A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.

Authors:  Randall J Brezski; Michelle Kinder; Katharine D Grugan; Keri L Soring; Jill Carton; Allison R Greenplate; Theodore Petley; Dorie Capaldi; Kerry Brosnan; Eva Emmell; Sharon Watson; Robert E Jordan
Journal:  MAbs       Date:  2014-10-30       Impact factor: 5.857

2.  Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes.

Authors:  Rui Yang; Marielle A Otten; Thomas Hellmark; Mattias Collin; Lars Björck; Ming-Hui Zhao; Mohamed R Daha; Mårten Segelmark
Journal:  Nephrol Dial Transplant       Date:  2010-03-10       Impact factor: 5.992

3.  Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.

Authors:  Willem J J Falkenburg; Dirkjan van Schaardenburg; Pleuni Ooijevaar-de Heer; Michel W P Tsang-A-Sjoe; Irene E M Bultink; Alexandre E Voskuyl; Arthur E H Bentlage; Gestur Vidarsson; Gertjan Wolbink; Theo Rispens
Journal:  J Immunol       Date:  2016-11-18       Impact factor: 5.422

4.  Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study.

Authors:  Fredrik Uhlin; Wladimir Szpirt; Andreas Kronbichler; Annette Bruchfeld; Inga Soveri; Lionel Rostaing; Eric Daugas; Arnaud Lionet; Nassim Kamar; Cédric Rafat; Marek Mysliveček; Vladimír Tesař; Anders Fernström; Christian Kjellman; Charlotte Elfving; Stephen McAdoo; Johan Mölne; Ingeborg Bajema; Elisabeth Sonesson; Mårten Segelmark
Journal:  J Am Soc Nephrol       Date:  2022-03-08       Impact factor: 14.978

5.  Human F(ab')2-containing immune complexes together with anti-hinge natural antibodies stimulate complement amplification in vitro and in vivo.

Authors:  Sandra Fumia; Jeroen S Goede; Manuel Fischler; Alexander Luginbühl; Sonia Frick; Patricia Fodor; Hans U Lutz
Journal:  Mol Immunol       Date:  2008-03-14       Impact factor: 4.407

  5 in total

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