OBJECTIVE: This study aimed to analyze the association between self-reported symptoms and seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the population of Mato Grosso. METHODS: A household-based survey was conducted on 4,206 adults from 10 municipalities of Mato Grosso, in the Brazilian Midwest, who were selected by cluster sampling in three stages. Questionnaires were applied between September and October 2020, and chemiluminescence was used for the quantitative determination of immunoglobulin G (IgG) antibodies against the S1 and S2 proteins of SARS-CoV-2. RESULTS: Approximately half (47.0%) of individuals with SARS-CoV-2 antibodies (12.5%) reported having no symptoms. The most prevalent symptoms among individuals with antibodies were body pain (37.0%), fever (32.9%), and smell and taste change (28.7%). The search for a basic health unit was predominant (45.0%) as the first service, and only 5.3% reported being hospitalized. CONCLUSION: A high proportion of asymptomatic cases of coronavirus disease 2019 (COVID-19) was identified in the general population, even among older adults and individuals with comorbidities.
OBJECTIVE: This study aimed to analyze the association between self-reported symptoms and seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the population of Mato Grosso. METHODS: A household-based survey was conducted on 4,206 adults from 10 municipalities of Mato Grosso, in the Brazilian Midwest, who were selected by cluster sampling in three stages. Questionnaires were applied between September and October 2020, and chemiluminescence was used for the quantitative determination of immunoglobulin G (IgG) antibodies against the S1 and S2 proteins of SARS-CoV-2. RESULTS: Approximately half (47.0%) of individuals with SARS-CoV-2 antibodies (12.5%) reported having no symptoms. The most prevalent symptoms among individuals with antibodies were body pain (37.0%), fever (32.9%), and smell and taste change (28.7%). The search for a basic health unit was predominant (45.0%) as the first service, and only 5.3% reported being hospitalized. CONCLUSION: A high proportion of asymptomatic cases of coronavirus disease 2019 (COVID-19) was identified in the general population, even among older adults and individuals with comorbidities.
Authors: Jan C Luers; Alexander C Rokohl; Niklas Loreck; Philomena A Wawer Matos; Max Augustin; Felix Dewald; Florian Klein; Clara Lehmann; Ludwig M Heindl Journal: Clin Infect Dis Date: 2020-11-19 Impact factor: 9.079
Authors: X Wang; J Fang; Y Zhu; L Chen; F Ding; R Zhou; L Ge; F Wang; Q Chen; Y Zhang; Q Zhao Journal: Clin Microbiol Infect Date: 2020-04-03 Impact factor: 8.067
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Authors: Qun Li; Xuhua Guan; Peng Wu; Xiaoye Wang; Lei Zhou; Yeqing Tong; Ruiqi Ren; Kathy S M Leung; Eric H Y Lau; Jessica Y Wong; Xuesen Xing; Nijuan Xiang; Yang Wu; Chao Li; Qi Chen; Dan Li; Tian Liu; Jing Zhao; Man Liu; Wenxiao Tu; Chuding Chen; Lianmei Jin; Rui Yang; Qi Wang; Suhua Zhou; Rui Wang; Hui Liu; Yinbo Luo; Yuan Liu; Ge Shao; Huan Li; Zhongfa Tao; Yang Yang; Zhiqiang Deng; Boxi Liu; Zhitao Ma; Yanping Zhang; Guoqing Shi; Tommy T Y Lam; Joseph T Wu; George F Gao; Benjamin J Cowling; Bo Yang; Gabriel M Leung; Zijian Feng Journal: N Engl J Med Date: 2020-01-29 Impact factor: 176.079
Authors: Michael A Johansson; Talia M Quandelacy; Sarah Kada; Pragati Venkata Prasad; Molly Steele; John T Brooks; Rachel B Slayton; Matthew Biggerstaff; Jay C Butler Journal: JAMA Netw Open Date: 2021-01-04
Authors: Ana M B Menezes; Cesar G Victora; Fernando P Hartwig; Mariângela F Silveira; Bernardo L Horta; Aluísio J D Barros; Marilia A Mesenburg; Fernando C Wehrmeister; Lúcia C Pellanda; Odir A Dellagostin; Cláudio J Struchiner; Marcelo N Burattini; Fernando C Barros; Pedro C Hallal Journal: Sci Rep Date: 2021-06-24 Impact factor: 4.379