Literature DB >> 359459

Influence of calcium, magnesium, lanthanum and A23187 on the aggregation of polymorphonuclear neutrophils.

J T O'Flaherty, H J Showell, P A Ward.   

Abstract

Chemotactic factors transiently aggregate human polymorphonuclear neutrophils. We have found that the aggregation induced by the chemotactic tripeptide, formyl-methionyl-leucyl-phenylalanine, depends on the extracellular calcium and magnesium concentrations and is inhibited by 1 and 10 M lanthanum chloride. The ionophore A23187 and 1 and 0.1 mM lanthanum chloride aggregate the cells. A23187-induced aggregation is dependent on extracellular calcium and magnesium whereas lanthanum-induced aggregation is not.

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Year:  1978        PMID: 359459     DOI: 10.3109/08820137809025480

Source DB:  PubMed          Journal:  Immunol Commun        ISSN: 0090-0877


  4 in total

1.  Comparison of the calcium ionophore and phorbol myristate acetate on the initiation of the respiratory burst in human neutrophils.

Authors:  L R DeChatelet; C J Lees; C E Walsh; G D Long; P S Shirley
Journal:  Infect Immun       Date:  1982-12       Impact factor: 3.441

2.  Lymphokine-induced macrophage aggregation: involvement of cyclic-GMP and microtubules.

Authors:  B Rouveix; S Larno; P Badenoch-Jones; P Lechat
Journal:  Agents Actions       Date:  1981-12

3.  Effect of calcium, magnesium, and cytochalasin B on arachidonic acid-induced neutrophil aggregation.

Authors:  J T O'Flaherty
Journal:  Inflammation       Date:  1980-03       Impact factor: 4.092

4.  Selective neutrophil desensitization to chemotactic factors.

Authors:  J T O'Flaherty; D L Kreutzer; H J Showell; G Vitkauskas; E L Becker; P A Ward
Journal:  J Cell Biol       Date:  1979-03       Impact factor: 10.539

  4 in total

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