Literature DB >> 35944976

Housing and Husbandry Alternatives for Naked Mole Rat Colonies Used in Research Settings.

Natalie H Ragland1, Nicole R Compo2, Norman Wiltshire2, Alyssa Shepard3, Scott Troutman3, Joseph L Kissil3, Robert W Engelman2.   

Abstract

Naked mole rats (Heterocephalus glaber) are a unique rodent species originating in Africa and are increasingly being used in research. Their needs and characteristics differ from those of other rodents used in research. Unique housing systems are necessary to address the special macro- and microenvironmental requirements of NMRs. Naked mole rats are one of the 2 known eusocial mammalian species, are extremely long-living, are active burrowers, and are accustomed to a subterranean environment. Unlike typical rats and mice, naked mole rats need specific, unique housing systems that mimic their natural subterranean environment to support health and longevity. Here we provide an overview of naked mole rats and a housing method that can be used in research settings.

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Year:  2022        PMID: 35944976      PMCID: PMC9536831          DOI: 10.30802/AALAS-JAALAS-22-000035

Source DB:  PubMed          Journal:  J Am Assoc Lab Anim Sci        ISSN: 1559-6109            Impact factor:   1.706


  39 in total

1.  Nest Carbon Dioxide Masks GABA-Dependent Seizure Susceptibility in the Naked Mole-Rat.

Authors:  Michael Zions; Edward F Meehan; Michael E Kress; Donald Thevalingam; Edmund C Jenkins; Kai Kaila; Martin Puskarjov; Dan P McCloskey
Journal:  Curr Biol       Date:  2020-04-30       Impact factor: 10.834

2.  Functional, Morphological, and Evolutionary Characterization of Hearing in Subterranean, Eusocial African Mole-Rats.

Authors:  Sonja J Pyott; Marcel van Tuinen; Laurel A Screven; Katrina M Schrode; Jun-Ping Bai; Catherine M Barone; Steven D Price; Anna Lysakowski; Maxwell Sanderford; Sudhir Kumar; Joseph Santos-Sacchi; Amanda M Lauer; Thomas J Park
Journal:  Curr Biol       Date:  2020-09-03       Impact factor: 10.834

3.  Molecular evolution of the hyaluronan synthase 2 gene in mammals: implications for adaptations to the subterranean niche and cancer resistance.

Authors:  Christopher G Faulkes; Kalina T J Davies; Stephen J Rossiter; Nigel C Bennett
Journal:  Biol Lett       Date:  2015-05       Impact factor: 3.703

Review 4.  The use of non-traditional models in the study of cancer resistance-the case of the naked mole rat.

Authors:  Alyssa Shepard; Joseph L Kissil
Journal:  Oncogene       Date:  2020-06-13       Impact factor: 9.867

Review 5.  Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species.

Authors:  Rochelle Buffenstein
Journal:  J Comp Physiol B       Date:  2008-01-08       Impact factor: 2.200

6.  The Naked Mole-Rat: An Unusual Organism with an Unexpected Latent Potential for Increased Intelligence?

Authors:  Dirk Schulze-Makuch
Journal:  Life (Basel)       Date:  2019-09-16

7.  Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.

Authors:  Masaki Takasugi; Denis Firsanov; Gregory Tombline; Hanbing Ning; Julia Ablaeva; Andrei Seluanov; Vera Gorbunova
Journal:  Nat Commun       Date:  2020-05-12       Impact factor: 14.919

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