Literature DB >> 3594418

Proximal 3p deletion in renal cell carcinoma cells from a patient with von Hippel-Lindau disease.

C R King, R N Schimke, T Arthur, B Davoren, D Collins.   

Abstract

A case of proximal 3p deletion is reported in tumor cells from a patient with renal cell carcinoma and von Hippel-Lindau disease. This is the first report of this deletion with renal cell carcinoma. With the previously detected translocations at the same breakpoint, this report confirms the 3p14 breakpoint as critical in this neoplasm. This strongly suggests that renal cell carcinoma results from a change in the genetic material in the proximal short arm of chromosome #3.

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Year:  1987        PMID： 3594418     DOI： 10.1016/0165-4608(87)90017-3

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  5 in total

Review 1.  Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors.

Authors:  G Kovacs
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

2.  Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma.

Authors:  E R Maher; J R Yates; M A Ferguson-Smith
Journal:  J Med Genet       Date:  1990-05       Impact factor: 6.318

3.  Cytogenetic studies on three pheochromocytomas derived from patients with von Hippel-Lindau syndrome.

Authors:  M Kiechle-Schwarz; H P Neumann; H J Decker; C Dietrich; B Wullich; W Schempp
Journal:  Hum Genet       Date:  1989-05       Impact factor: 4.132

4.  Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinomas.

Authors:  G Kovacs; H F Kung
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

5.  Familial renal cell carcinoma: clinical and molecular genetic aspects.

Authors:  E R Maher; J R Yates
Journal:  Br J Cancer       Date:  1991-02       Impact factor: 7.640
  5 in total

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