Literature DB >> 3594121

Splenectomy in the management of haematological disease.

A A Dawson, P F Jones, D J King.   

Abstract

Patients, both adults and children, with various haematological disorders who had splenectomy electively in the diagnosis, staging or treatment of their condition during a 15-year period in the Aberdeen hospitals were reviewed. The outcome regarding the disease and the immediate and long-term complications of splenectomy in this group of 185 patients are presented. Splenectomy has an acceptably low morbidity, even in patients with serious haematological disease, in the hands of an experienced surgical team, where there is close co-operation between surgeon and haematologist. Occasionally, late overwhelming infections may occur, despite prophylaxis with penicillin and pneumococcal vaccination. It seems likely that, in their zeal to report such hazards, authors may allow the pendulum against splenectomy to swing too far, in the direction of leaving patients, especially adults, with considerable symptoms and poor health, rather than risk the occasional consequences of the asplenic state.

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Year:  1987        PMID: 3594121     DOI: 10.1002/bjs.1800740508

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  7 in total

1.  Immune profile of asplenic patients following single or double vaccine administration: A longitudinal cross-sectional study.

Authors:  Sait Murat Doğan; Ahmet Aykas; Evrim Şefika Yücel; Gökalp Okut; Cenk Şimşek; Kürşat Çayhan; Baha Zengel; Adam Uslu
Journal:  Ulus Cerrahi Derg       Date:  2015-04-09

Review 2.  [Role of the spleen in tumor surgery].

Authors:  U Wolters; H W Keller; H Pichlmaier
Journal:  Langenbecks Arch Chir       Date:  1991

3.  Splenectomy in hematologic disorders. The ever-changing indications.

Authors:  M C Wilhelm; R E Jones; R McGehee; J S Mitchener; W R Sandusky; C E Hess
Journal:  Ann Surg       Date:  1988-05       Impact factor: 12.969

4.  Splenectomy in children with sickle cell disease and thalassemia.

Authors:  A H al-Salem; M S Khwaja; M al-Fadel; C Grant; B al Awami
Journal:  Indian J Pediatr       Date:  1989 Nov-Dec       Impact factor: 1.967

5.  Laparoscopic splenectomy in patients with hematologic diseases.

Authors:  J L Flowers; A T Lefor; J Steers; M Heyman; S M Graham; A L Imbembo
Journal:  Ann Surg       Date:  1996-07       Impact factor: 12.969

6.  Postoperative complications after splenectomy for hematologic malignancies.

Authors:  J Horowitz; J L Smith; T K Weber; M A Rodriguez-Bigas; N J Petrelli
Journal:  Ann Surg       Date:  1996-03       Impact factor: 12.969

7.  Minimal role for the spleen in antibody responses of C57BR/cdj mice to pneumococcal polysaccharide antigens.

Authors:  D A Cohn; G Schiffman
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

  7 in total

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